Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 12/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19492619 | 0.89 | KCNH2 (0.33) | KDM4CMTNR1AMTNR1BKCNH2 | |
| SCHEMBL19492795 | 0.81 | MAPK1 (0.40) | MAPK1 | |
| SCHEMBL20768124 | 0.81 | MAPK1 (0.40) | MAPK1 | |
| SCHEMBL19492493 | 0.77 | — | — | |
| SCHEMBL19492649 | 0.74 | PDE2A (0.36) | KDM4CMTNR1AMTNR1B | |
| SCHEMBL19492669 | 0.74 | KDM4C (0.38) | KDM4CKDM6BMAPT | |
| SCHEMBL19492642 | 0.73 | PDE2A (0.34) | KDM4CMTNR1AMTNR1BMAPT | |
| SCHEMBL19492758 | 0.73 | MTNR1A (0.39) | MTNR1AMTNR1BKDM4EALDH1A1MAPT | |
| SCHEMBL19492647 | 0.72 | KDM4C (0.36) | KDM4C | |
| SCHEMBL19492620 | 0.71 | BRD4 (0.41) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017178416-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2017-10-19 | — | — | WO | disclosed |