Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19463513 | 0.85 | KDM4E (0.50) | ALDH1A1KDM4EMAPTHSD17B10TSHR | |
| SCHEMBL19493121 | 0.76 | KDM4E (0.43) | ALDH1A1KDM4EMAPTCRHR1TSHR | |
| SCHEMBL19492617 | 0.71 | KDM4E (0.48) | ALDH1A1KDM4EMAPTHSD17B10TSHR | |
| SCHEMBL19492633 | 0.71 | KDM4E (0.53) | ALDH1A1KDM4EMAPTHSD17B10TSHR | |
| SCHEMBL19492504 | 0.70 | KDM4E (0.56) | ALDH1A1KDM4EMAPTHSD17B10TSHR | |
| SCHEMBL19464037 | 0.70 | KDM4E (0.52) | ALDH1A1KDM4EMAPTHSD17B10TSHR | |
| SCHEMBL19492634 | 0.69 | KDM4E (0.51) | ALDH1A1KDM4EMAPTHSD17B10TSHR | |
| SCHEMBL19464210 | 0.69 | KDM4E (0.48) | ALDH1A1KDM4EMAPTHSD17B10TSHR | |
| SCHEMBL19463663 | 0.68 | KDM4E (0.50) | ALDH1A1KDM4EMAPTHSD17B10TSHR | |
| SCHEMBL19463510 | 0.68 | ALDH1A1 (0.56) | ALDH1A1KDM4EMAPTHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017178416-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2017-10-19 | — | — | WO | disclosed |