Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.38 |
| ▸ | CNR1 | P21554 | 6/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1949516 | 0.93 | CNR2 (0.38) | CNR2CNR1PKMLMNAPOLB | |
| SCHEMBL1949726 | 0.88 | PARP1 (0.43) | CNR2CNR1PKMLMNAPOLB | |
| SCHEMBL1948479 | 0.84 | MEN1 (0.41) | CNR2CNR1PKMLMNAPOLB | |
| SCHEMBL1948760 | 0.80 | CNR2 (0.36) | CNR2CNR1PKMLMNAPOLB | |
| SCHEMBL1949371 | 0.78 | NOTUM (0.47) | PKMLMNAPOLBALDH1A1GAA | |
| SCHEMBL1950087 | 0.78 | CNR2 (0.37) | CNR2CNR1PKMLMNAPOLB | |
| SCHEMBL1948776 | 0.77 | CNR2 (0.40) | CNR2CNR1PKMLMNAPOLB | |
| SCHEMBL1951619 | 0.77 | PARP11 (0.45) | HTR2CHTR7 | |
| SCHEMBL1946931 | 0.77 | MEN1 (0.41) | CNR2CNR1PKMLMNAPOLB | |
| SCHEMBL1950702 | 0.76 | NOTUM (0.47) | LMNAPOLBALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110136860-A1 | Compounds | XENTION LTD. (GB) | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136860-A1 | Compounds | NR3C2, NR5A1, NR0B2 | CNR2 90/4885CNR1 21/4885PKM 3746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.