Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19495011 | 0.85 | ABCB1 (0.35) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL19494852 | 0.82 | KDM4E (0.41) | KDM4EPOLBFTOABCB1USP2 | |
| SCHEMBL19655017 | 0.80 | FTO (0.39) | KDM4EPOLBFTOABCB1USP2 | |
| SCHEMBL26472325 | 0.79 | FTO (0.42) | KDM4EPOLBFTOABCB1USP2 | |
| SCHEMBL13295495 | 0.78 | ABCB1 (0.41) | KDM4EPOLBFTOABCB1USP2 | |
| SCHEMBL20858848 | 0.77 | CA9 (0.41) | FTOABCB1USP2CFTRPAX8 | |
| SCHEMBL16593493 | 0.76 | CA9 (0.40) | FTOABCB1USP2CFTRPAX8 | |
| SCHEMBL29822272 | 0.76 | FTO (0.40) | KDM4EPOLBFTOABCB1USP2 | |
| SCHEMBL19655014 | 0.76 | FTO (0.40) | KDM4EPOLBFTOABCB1USP2 | |
| SCHEMBL16593491 | 0.76 | CA9 (0.40) | FTOABCB1USP2CFTRPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3235876-A1 | QUENCHER | Wako Pure Chemical Industries, Ltd. (JP) | 2017-10-25 | — | — | EP | disclosed |