Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | CASP1 | P29466 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CASP7 | P55210 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 10/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12043100 | 0.81 | MEN1 (0.69) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14073364 | 0.76 | ALDH1A1 (0.70) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2525573 | 0.74 | KDM4E (0.84) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19495014 | 0.73 | KDM4E (0.58) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12043094 | 0.70 | KDM4E (0.85) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16940595 | 0.70 | KDM4E (0.74) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12043118 | 0.69 | ALDH1A1 (0.70) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12043096 | 0.69 | MEN1 (0.81) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5014910 | 0.68 | KDM4E (0.72) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14073368 | 0.68 | KDM4E (0.64) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937252-B1 | COMPOSITIONS FOR STIMULATING NEUROGENESIS AND INHIBITING NEURONAL DEGENERATION | NEURONASCENT INC (US) | 2017-10-25 | — | — | EP | disclosed |