Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 16/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 14/20 | 0.55 |
| ▸ | MAPK8 | P45983 | 13/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GLS | O94925 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19495352 | 0.77 | MAPK9 (0.69) | MAPK9MAPK10MAPK8MAPK1GLS | |
| SCHEMBL3783257 | 0.71 | MAPK9 (1.00) | MAPK9MAPK10MAPK8MAPK1 | |
| SCHEMBL3714663 | 0.67 | MAPK9 (0.65) | MAPK9MAPK10MAPK8MAPK1GLS | |
| SCHEMBL3710279 | 0.65 | MAPK9 (0.81) | MAPK9MAPK10MAPK8MAPK1GLS | |
| SCHEMBL3720399 | 0.64 | KDM4E (0.59) | MAPK9MAPK10MAPK8GLSALDH1A1 | |
| SCHEMBL3782088 | 0.64 | MAPK9 (1.00) | MAPK9MAPK10MAPK8MAPK1 | |
| SCHEMBL3776306 | 0.64 | MAPK9 (1.00) | MAPK9MAPK10MAPK8MAPK1 | |
| SCHEMBL3777866 | 0.64 | MAPK10 (1.00) | MAPK9MAPK10MAPK8MAPK1 | |
| SCHEMBL21484424 | 0.64 | GLS (1.00) | GLS | |
| SCHEMBL3783847 | 0.63 | GLS (0.49) | MAPK9MAPK10MAPK8GLSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393806-B1 | INHIBITORS OF JUN N-TERMINAL KINASE | ELAN PHARM INC (US) | 2017-10-25 | — | — | EP | disclosed |