Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | FDPS | P14324 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.48 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.48 |
| ▸ | ABAT | P80404 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7677018 | 0.86 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2TSHRPOLBFDPS | |
| SCHEMBL1950408 | 0.84 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2POLBFDPSKDM4E | |
| SCHEMBL1949645 | 0.83 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2TSHRPOLBFDPS | |
| SCHEMBL2560660 | 0.81 | ALDH1A1 (0.78) | ALDH1A1SMN1; SMN2TSHRPOLBFDPS | |
| SCHEMBL29956334 | 0.81 | POLB (0.65) | ALDH1A1SMN1; SMN2TSHRPOLBFDPS | |
| SCHEMBL5246469 | 0.81 | POLB (0.65) | ALDH1A1SMN1; SMN2TSHRPOLBFDPS | |
| SCHEMBL2284391 | 0.80 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2TSHRPOLBFDPS | |
| SCHEMBL2556412 | 0.80 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2TSHRPOLBFDPS | |
| SCHEMBL2559017 | 0.80 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2TSHRPOLBFDPS | |
| SCHEMBL2555761 | 0.78 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2TSHRPOLBFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2507237-A1 | IMIDAZOQUINOLINES WHICH ACT VIA TOLL - LIKE RECEPTORS (TLR) | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2012-10-10 | — | — | EP | disclosed |
| WO-2011068233-A1 | IMIDAZOQUINOLINES WHICH ACT VIA TOLL - LIKE RECEPTORS (TLR) | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2011-06-09 | — | — | WO | disclosed |
| US-20110136801-A1 | Novel Compounds | DAINIPPON SUMITOMO PHARMA CO. LTD. (JP) | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136801-A1 | Novel Compounds | C1R, RB1, CNKSR1 | ALDH1A1 173/4885SMN1; SMN2 1340/4885TSHR 185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.