Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 11/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11368219 | 0.88 | AOC3 (0.74) | AOC3 | |
| SCHEMBL11365328 | 0.81 | AOC3 (0.54) | AOC3GAAKDM4EALDH1A1HPGD | |
| SCHEMBL11360895 | 0.74 | AOC3 (0.77) | AOC3 | |
| SCHEMBL11363430 | 0.74 | AOC3 (0.76) | AOC3 | |
| SCHEMBL28871986 | 0.73 | SMN1; SMN2 (0.56) | GAAKDM4EALDH1A1HPGDCHRNB2 | |
| SCHEMBL28923681 | 0.73 | GAA (0.58) | GAAKDM4EALDH1A1HPGDCHRNB2 | |
| SCHEMBL15986659 | 0.72 | AOC3 (0.48) | AOC3 | |
| SCHEMBL17478640 | 0.72 | SMN1; SMN2 (0.69) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL17559747 | 0.71 | SMN1; SMN2 (0.60) | GAAKDM4EALDH1A1HPGDCHRNB2 | |
| SCHEMBL10320682 | 0.71 | AOC3 (0.74) | AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2479165-B1 | GLYCINE COMPOUND | ASTELLAS PHARMA INC (JP) | 2017-10-25 | — | — | EP | disclosed |