Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 7/20 | 0.52 |
| ▸ | FYN | P06241 | 2/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.48 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | TNKS | O95271 | 3/20 | 0.47 |
| ▸ | SMO | Q99835 | 1/20 | 0.47 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19497006 | 0.88 | NTRK1 (0.53) | AOC3CNR2SMOMAP4K1 | |
| SCHEMBL19496801 | 0.84 | AOC3 (0.59) | AOC3CNR2TNKSSMO | |
| SCHEMBL11364473 | 0.83 | AOC3 (0.74) | AOC3 | |
| SCHEMBL22792254 | 0.82 | SMO (0.56) | SMOMAP4K1HTR3A | |
| SCHEMBL19496775 | 0.81 | AOC3 (0.59) | AOC3CNR2SMO | |
| SCHEMBL15344195 | 0.81 | FYN (0.53) | FYNPRMT5WDR77CNR2TNKS | |
| SCHEMBL19496840 | 0.81 | AOC3 (0.52) | AOC3 | |
| SCHEMBL19496568 | 0.81 | AOC3 (0.52) | AOC3 | |
| SCHEMBL19496641 | 0.81 | AOC3 (0.52) | AOC3 | |
| SCHEMBL19496981 | 0.81 | AOC3 (0.49) | AOC3CNR2SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2479165-B1 | GLYCINE COMPOUND | ASTELLAS PHARMA INC (JP) | 2017-10-25 | — | — | EP | disclosed |