Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 12/20 | 0.59 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | SMO | Q99835 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11362192 | 0.86 | AOC3 (0.82) | AOC3 | |
| Hydrochloric Acid SCHEMBL10318458 | 0.85 | AOC3 (0.81) | AOC3 | |
| Hydrochloric Acid SCHEMBL10318459 | 0.85 | AOC3 (0.63) | AOC3 | |
| SCHEMBL19496818 | 0.84 | AOC3 (0.52) | AOC3CNR2SMOTNKS | |
| SCHEMBL19497006 | 0.80 | NTRK1 (0.53) | AOC3CNR2SMONTRK1 | |
| SCHEMBL19496809 | 0.77 | DGAT1 (0.50) | AOC3CNR2SMONTRK1 | |
| SCHEMBL19496527 | 0.77 | AOC3 (0.53) | AOC3ALDH1A1KDM4E | |
| SCHEMBL19496981 | 0.76 | AOC3 (0.49) | AOC3CNR2SMO | |
| SCHEMBL19496747 | 0.76 | AOC3 (0.58) | AOC3 | |
| SCHEMBL19496539 | 0.75 | AOC3 (0.60) | AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2479165-B1 | GLYCINE COMPOUND | ASTELLAS PHARMA INC (JP) | 2017-10-25 | — | — | EP | disclosed |