Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6673091 | 0.96 | HTR6 (0.53) | HTR6HTR2AKDM4ELMNATP53 | |
| SCHEMBL6675770 | 0.94 | HTR6 (0.51) | HTR6HTR2AKDM4ELMNATP53 | |
| SCHEMBL6675371 | 0.94 | HTR6 (0.51) | HTR6HTR2AKDM4ELMNATP53 | |
| SCHEMBL668105 | 0.91 | HTR6 (0.56) | HTR6HTR2AKDM4ELMNATP53 | |
| SCHEMBL8857119 | 0.89 | HTR2A (0.46) | HTR6HTR2AKDM4ELMNATP53 | |
| SCHEMBL20952390 | 0.89 | HTR6 (0.55) | HTR6HTR2AKDM4ELMNATP53 | |
| SCHEMBL5604259 | 0.89 | HTR6 (0.55) | HTR6HTR2AKDM4ELMNATP53 | |
| SCHEMBL4004561 | 0.89 | HTR6 (0.55) | HTR6HTR2AKDM4ELMNATP53 | |
| SCHEMBL8770696 | 0.89 | HTR6 (0.55) | HTR6HTR2AKDM4ELMNATP53 | |
| SCHEMBL9144867 | 0.89 | HTR6 (0.55) | HTR6HTR2AKDM4ELMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1706437-B1 | DUAL METALLOCENE CATALYST FOR PRODUCING FILM RESINS WITH GOOD MACHINE DIRECTION (MD) ELMENDORF TEAR STRENGTH | CHEVRON PHILLIPS CHEMICAL CO (US) | 2016-01-20 | — | — | EP | disclosed |
| US-20110137060-A1 | PREPARATION OF ANSA METALLOCENE COMPOUNDS | BASELL POLYOLEFIN GMBH (DE) | 2011-06-09 | — | — | US | disclosed |
| US-7572875-B2 | Ethylene homopolymers or copolymers having good machine direction (MD) elmendorf tear strength | CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) | 2009-08-11 | — | — | US | disclosed |
| US-20060229420-A1 | Ethylene homopolymers or copolymers having good machine direction (MD) elmendorf tear strength | CHEVRON PHILLIPS CHEMICAL COMPANY, LP | 2006-10-12 | — | — | US | disclosed |
| US-7119153-B2 | Dual metallocene catalyst for producing film resins with good machine direction (MD) elmendorf tear strength | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2006-10-10 | — | — | US | disclosed |
| EP-1706377-A1 | CIS-ALKOXYSPIRO-SUBSTITUTED TETRAMIC ACID DERIVATIVES | Bayer CropScience Aktiengesellschaft (DE) | 2006-10-04 | — | — | EP | disclosed |
| EP-1706437-A1 | DUAL METALLOCENE CATALYST FOR PRODUCING FILM RESINS WITH GOOD MACHINE DIRECTION (MD) ELMENDORF TEAR STRENGTH | Chevron Phillips Chemical Company LP (US) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005070977-A1 | DUAL METALLOCENE CATALYST FOR PRODUCING FILM RESINS WITH GOOD MACHINE DIRECTION (MD) ELMENDORF TEAR STRENGTH | CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) | 2005-08-04 | — | — | WO | disclosed |
| EP-1049704-B1 | BRIDGED METALLOCENES, PREPARATION, USE IN CATALYTIC SYSTEMS | BASELL POLYOLEFINE GMBH (DE) | 2005-07-27 | — | — | EP | disclosed |
| US-20050159300-A1 | Dual metallocene catalyst for producing film resins with good machine direction (MD) elmendorf tear strength | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2005-07-21 | — | — | US | disclosed |
| WO-2005066125-A1 | CIS-ALKOXYSPIRO-SUBSTITUTED TETRAMIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2005-07-21 | — | — | WO | disclosed |
| EP-0963990-B1 | PROCESS FOR PRODUCING CYCLOPENTADIENYL METAL SALTS AND PROCESS FOR PRODUCING CYCLOPENTADIENE DERIVATIVES BY UTILIZING THE SAME | SUMITOMO CHEMICAL CO (JP) | 2004-10-06 | — | — | EP | disclosed |
| US-6433203-B1 | COORDINATION POLYMERIZATION CATALYST; ALPHA-OLEFIN POLYMER | BASELL TECHNOLOGY COMPANY BV (NL) | 2002-08-13 | — | — | US | disclosed |
| US-6197990-B1 | REACTING CYCLOPENTADIENE AND METAL HYDRIDE IN PRESENCE OF AMINE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-03-06 | — | — | US | disclosed |
| EP-1049704-A1 | BRIDGED METALLOCENES, PREPARATION, USE IN CATALYTIC SYSTEMS | Montell Technology Company bv (NL) | 2000-11-08 | — | — | EP | disclosed |
| WO-2000031088-A1 | BRIDGED METALLOCENES, PREPARATION, USE IN CATALYTIC SYSTEMS | MONTELL TECHNOLOGY COMPANY BV (NL) | 2000-06-02 | — | — | WO | disclosed |
| EP-0963990-A1 | PROCESS FOR PRODUCING CYCLOPENTADIENYL METAL SALTS AND PROCESS FOR PRODUCING CYCLOPENTADIENE DERIVATIVES BY UTILIZING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-12-15 | — | — | EP | disclosed |
| US-5824618-A | TITANIUM COMPOUND, GROUP 1-3 COMPOUND, ORGANOCYCLIC COMPOUND | NIPPON OIL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110137060-A1 | PREPARATION OF ANSA METALLOCENE COMPOUNDS | NCL, ARSA, NASP | HTR6 4225/4885HTR2A 3836/4885KDM4E 3749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.