SCHEMBL1950

SCHEMBL1950

N#Cc1ccc(C(=O)Cl)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.61
CA1 P00915 2/20 0.61
GSK3B P49841 2/20 0.55
PARP15 Q460N3 1/20 0.50
PARP10 Q53GL7 1/20 0.50
PARP2 Q9UGN5 1/20 0.50
CA12 O43570 1/20 0.48
CA3 P07451 1/20 0.48
CA6 P23280 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
ALDH1A1 P00352 3/20 0.47
MAPT P10636 2/20 0.47
LMNA P02545 1/20 0.46
TSHR P16473 1/20 0.46
HTT P42858 1/20 0.46
NLRP3 Q96P20 1/20 0.46
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
NPC1 O15118 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28598773 0.98 CA2 (0.59) CA2CA1GSK3BPARP15PARP10
Hydrochloric Acid SCHEMBL5264593 0.98 CA2 (0.59) CA2CA1GSK3BPARP15PARP10
SCHEMBL9259021 0.94 CA2 (0.55) CA2CA1GSK3BPARP15PARP10
Methylene Chloride SCHEMBL27581417 0.94 CA2 (0.55) CA2CA1GSK3BPARP15PARP10
Terephthalic Acid SCHEMBL29224034 0.92 CA2 (0.53) CA2CA1GSK3BPARP15PARP10
Benzonitrile SCHEMBL27592558 0.92 TSHR (0.56) CA2CA1GSK3BPARP15PARP10
Alcohol SCHEMBL27617595 0.90 CA1 (0.52) CA2CA1GSK3BPARP15PARP10
SCHEMBL8733233 0.82 CA1 (0.44) CA2CA1GSK3BALDH1A1MAPT
SCHEMBL8676008 0.81 HTT (0.54) CA2CA1GSK3BALDH1A1MAPT
SCHEMBL3433075 0.80 CA2 (0.67) CA2CA1GSK3BPARP15PARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2936 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120020115-A Process for the preparation of N- (alkyl-2-hydroxy) alkylamides and N-alkenylamides 中国石油化工股份有限公司 2025-05-20 CN claimed
CN-120020114-A Preparation method of N-alkenyl amide compound 中国石油化工股份有限公司 2025-05-20 CN claimed
CN-119683660-A Preparation method of high-purity battery-grade lithium fluoride 江苏新泰材料科技有限公司 2025-03-25 CN claimed
CN-119571514-A Moisture-absorbing sweat-permeable chenille yarn and production process thereof 江苏多来运纺织有限公司 2025-03-07 CN claimed
CN-119504911-A Cucurbitacin B ester derivative and application thereof in medicines for resisting various cancer cells 常州大学 2025-02-25 CN claimed
CN-119431424-A Silicon oxime ester-containing photoinitiator, preparation method and application thereof 常州强力先端电子材料有限公司 2025-02-14 CN claimed
CN-116410106-B Benzamide HBV capsid protein inhibitor and preparation method and application thereof 山东第二医科大学 2024-12-06 CN claimed
CN-118388407-A Gadolinium complex and preparation method and application thereof 中国科学院长春应用化学研究所 2024-07-26 CN claimed
EP-4136068-B1 A PROCESS FOR THE PREPARATION OF 4-CYANOBENZOYL CHLORIDES BASF SE (DE) 2024-07-10 EP claimed
CN-112851547-B Fluorene oxime ester compound, preparation method thereof and photosensitive resin composition 常州强力先端电子材料有限公司 2024-06-07 CN claimed
EP-0847994-B1 Process for the preparation of mixed anhydrides HOFFMANN LA ROCHE (CH) 2003-04-09 EP claimed
CN-1073080-C Process for mfg. mixed anhydrides HOFFMANN LA ROCHE AB F (CH) 2001-10-17 CN claimed
US-6262292-B1 FORMING CYANAOBENZALDEHYDE BY OXIDATION OF CYANOBENZYLAMINE SHOWA DENKO K.K. (JP) 2001-07-17 US claimed
EP-1083165-A1 PROCESSES FOR PRODUCING CYANOPHENYL DERIVATIVES Showa Denko Kabushiki Kaisha (JP) 2001-03-14 EP claimed
EP-0989115-A2 Process for producing cyanobenzoic acid derivatives Showa Denko Kabushiki Kaisha (JP) 2000-03-29 EP claimed
EP-0639559-B1 Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines ROHM & HAAS (US) 1997-10-15 EP claimed
EP-0639559-A1 Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines ROHM AND HAAS COMPANY (US) 1995-02-22 EP claimed
US-5357005-A Reactive surface functionalization INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1994-10-18 US claimed
WO-1993014055-A1 PREPARATION OF 2,5-DICHLOROBENZOPHENONES MAXDEM INCORPORATED (US) 1993-07-22 WO claimed
US-5210313-A Friedel crafts aryloylation of 1,4-dichlorobenzene and Lewis acids MAXDEM INCORPORATED (US) 1993-05-11 US claimed