Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.73 |
| ▸ | CETP | P11597 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.55 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19501631 | 0.89 | HPGD (0.87) | HPGDSMN1; SMN2GAAEPHX1EPHX2 | |
| SCHEMBL31401950 | 0.87 | HPGD (0.83) | HPGDSMN1; SMN2GAAEPHX1EPHX2 | |
| SCHEMBL12323604 | 0.87 | CETP (0.77) | HPGDCETPHDAC3HDAC1HDAC2 | |
| SCHEMBL28256535 | 0.87 | CETP (0.77) | HPGDCETPHDAC3HDAC1HDAC2 | |
| SCHEMBL28258088 | 0.87 | CETP (0.77) | HPGDCETPHDAC3HDAC1HDAC2 | |
| SCHEMBL8020697 | 0.86 | HPGD (0.71) | HPGDCETPHDAC3HDAC1HDAC2 | |
| SCHEMBL1300190 | 0.85 | HPGD (1.00) | HPGDGAAALDH1A1PTPN1KCNK3 | |
| SCHEMBL19703413 | 0.85 | HPGD (1.00) | HPGDGAAALDH1A1PTPN1KCNK3 | |
| SCHEMBL19501632 | 0.85 | HPGD (0.79) | HPGDSMN1; SMN2GAAEPHX1EPHX2 | |
| SCHEMBL4668488 | 0.84 | HPGD (0.96) | HPGDSMN1; SMN2GAARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10343438-B2 | Heat-sensitive recording material | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2019-07-09 | — | — | US | disclosed |
| US-20170297355-A1 | Heat-Sensitive Recording Material | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2017-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170297355-A1 | Heat-Sensitive Recording Material | SCN1A, SCN3A, KCNN3 | HPGD 1145/4885CETP 4720/4885HDAC3 1748/4885 |
| US-10343438-B2 | Heat-sensitive recording material | SCN1A, SCN3A, KCNN3 | HPGD 1145/4885CETP 4720/4885HDAC3 1748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.