SCHEMBL19502238

SCHEMBL19502238

CCCCC(CC)C(=O)OCCOc1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 4/20 0.49
PPARG P37231 4/20 0.49
PTGES O14684 3/20 0.49
PPARA Q07869 2/20 0.49
NPC1 O15118 4/20 0.46
RAB9A P51151 4/20 0.46
KDM4E B2RXH2 3/20 0.46
ALDH1A1 P00352 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
RARB P10826 4/20 0.45
NPSR1 Q6W5P4 1/20 0.45
LMNA P02545 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MAPT P10636 2/20 0.43
HPGD P15428 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
PLA2G2A P14555 1/20 0.42
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2608670 0.89 PPARG (0.43) ALOX5PPARGPTGESPPARANPC1
SCHEMBL29370811 0.89 PPARG (0.43) ALOX5PPARGPTGESPPARANPC1
SCHEMBL19240505 0.87 PTGES (0.44) ALOX5PPARGPTGESPPARANPSR1
SCHEMBL19502283 0.87 PPARG (0.42) ALOX5PPARGPTGESPPARANPC1
SCHEMBL13431002 0.87 TDP1 (0.54) ALOX5PPARGPTGESPPARANPC1
SCHEMBL13851798 0.86 PPARG (0.43) ALOX5PPARGPTGESPPARANPSR1
SCHEMBL26240776 0.85 PPARG (0.41) ALOX5PPARGPTGESPPARANPSR1
SCHEMBL17599779 0.85 GAA (0.41) ALOX5PPARGPTGESPPARANPSR1
SCHEMBL29069614 0.82 PTGES (0.41) ALOX5PPARGPTGESPPARAKDM4E
SCHEMBL12115325 0.81 NPSR1 (0.42) ALOX5PPARGPTGESPPARANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2474302-B1 SUNSCREEN COSMETIC COMPOSITION CONTAINING ULTRAVIOLET ABSORBER ADEKA CORP (JP) 2017-10-25 EP disclosed