Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84845 | 1.00 | PRCP (0.41) | PRCPDPP7NOS2NOS3NOS1 | |
| SCHEMBL7782161 | 1.00 | PRCP (0.41) | PRCPDPP7NOS2NOS3NOS1 | |
| Hydrochloric Acid SCHEMBL29401738 | 0.98 | PRCP (0.41) | PRCPDPP7NOS2NOS3NOS1 | |
| Hydrochloric Acid SCHEMBL16007350 | 0.98 | PRCP (0.41) | PRCPDPP7NOS2NOS3NOS1 | |
| Hydrochloric Acid SCHEMBL16007352 | 0.98 | PRCP (0.41) | PRCPDPP7NOS2NOS3NOS1 | |
| SCHEMBL5538288 | 0.94 | TSHR (0.40) | PRCPDPP7CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL7886550 | 0.94 | TSHR (0.40) | PRCPDPP7CYP3A4CYP2D6CYP1A2 | |
| Hydrochloric Acid SCHEMBL7886551 | 0.93 | TSHR (0.40) | PRCPCYP3A4CYP2D6CYP2C9TSHR | |
| SCHEMBL31008706 | 0.90 | TSHR (0.37) | PRCPNOS2NOS3NOS1TSHR | |
| SCHEMBL15391851 | 0.89 | PRCP (0.41) | PRCPDPP7NOS2NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10035791-B2 | Bicyclic compound and pharmaceutical composition thereof for treating stroke and use thereof | CHINA MEDICAL UNIVERSITY (TW) | 2018-07-31 | — | — | US | disclosed |
| US-20170298049-A1 | BICYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF FOR TREATING STROKE AND USE THEREOF | CHINA MEDICAL UNIVERSITY (TW) | 2017-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170298049-A1 | BICYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF FOR TREATING STROKE AND USE THEREOF | PCSK9, NDUFC2, PCSK7 | PRCP 719/4885DPP7 1134/4885NOS2 2011/4885 |
| US-10035791-B2 | Bicyclic compound and pharmaceutical composition thereof for treating stroke and use thereof | PCSK9, NDUFC2, PCSK7 | PRCP 719/4885DPP7 1134/4885NOS2 2011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.