Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5538288 | 1.00 | TSHR (0.40) | TSHRCYP3A4CYP2D6CYP2C9PRCP | |
| Hydrochloric Acid SCHEMBL7886551 | 0.98 | TSHR (0.40) | TSHRCYP3A4CYP2D6CYP2C9PRCP | |
| SCHEMBL84845 | 0.94 | PRCP (0.41) | TSHRCYP3A4CYP2D6CYP2C9PRCP | |
| SCHEMBL7782161 | 0.94 | PRCP (0.41) | TSHRCYP3A4CYP2D6CYP2C9PRCP | |
| SCHEMBL19502428 | 0.94 | PRCP (0.41) | TSHRCYP3A4CYP2D6CYP2C9PRCP | |
| Hydrochloric Acid SCHEMBL29401738 | 0.93 | PRCP (0.41) | CYP3A4CYP2D6PRCPDPP7CYP1A2 | |
| Hydrochloric Acid SCHEMBL16007350 | 0.93 | PRCP (0.41) | CYP3A4CYP2D6PRCPDPP7CYP1A2 | |
| Hydrochloric Acid SCHEMBL16007352 | 0.93 | PRCP (0.41) | CYP3A4CYP2D6PRCPDPP7CYP1A2 | |
| SCHEMBL31008706 | 0.88 | TSHR (0.37) | TSHRPRCPALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL29284089 | 0.86 | PRCP (0.36) | TSHRPRCPSLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1108053-A1 | METHOD FOR PREPARING (2R)-PIPERIDINE DERIVATIVES | LONZA A.G. (CH) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012745-A1 | METHOD FOR PREPARING (2R)-PIPERIDINE DERIVATIVES | LONZA AG (CH) | 2000-03-09 | — | — | WO | disclosed |