Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 6/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | FABP3 | P05413 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25643859 | 0.83 | KDM4E (0.42) | POLBLMNAHTTKDM4EATM | |
| SCHEMBL24727169 | 0.82 | KIF11 (0.36) | POLBMAPTGPR3KDM4EALDH1A1 | |
| SCHEMBL18774270 | 0.80 | POLB (0.48) | POLBLMNAMAPTHTTGPR3 | |
| SCHEMBL26215669 | 0.78 | KDM4E (0.36) | KDM4EATML3MBTL1 | |
| SCHEMBL19102262 | 0.77 | NR4A2 (0.35) | LMNAMAPTHTTKDM4EALDH1A1 | |
| SCHEMBL25976981 | 0.76 | POLB (0.44) | POLBLMNAMAPTHTTGPR3 | |
| SCHEMBL23119710 | 0.75 | DAO (0.43) | POLBMEN1KMT2A | |
| SCHEMBL23620797 | 0.75 | POLB (0.43) | POLBLMNAMAPTHTTGPR3 | |
| SCHEMBL18594222 | 0.73 | POLB (0.42) | POLBLMNAMAPTHTTGPR3 | |
| SCHEMBL16905940 | 0.73 | POLB (0.48) | POLBLMNAMAPTHTTGPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3232485-A1 | BENZIMIDAZO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ELECTRONIC APPLICATIONS | UDC Ireland Limited (IE) | 2017-10-18 | — | — | EP | disclosed |