Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 14/20 | 0.67 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.67 |
| ▸ | P2RY11 | Q96G91 | 3/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | NT5E | P21589 | 2/20 | 0.47 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16258261 | 0.93 | P2RY1 (0.66) | P2RY1P2RY2P2RY11ADORA1NT5E | |
| SCHEMBL21257386 | 0.88 | P2RY1 (0.70) | P2RY1P2RY2P2RY11ENPP1P2RY12 | |
| SCHEMBL19503299 | 0.88 | P2RY1 (0.69) | P2RY1P2RY2ADORA1NT5EADORA3 | |
| SCHEMBL19503298 | 0.87 | P2RY1 (0.70) | P2RY1P2RY2ADORA1NT5EADORA3 | |
| SCHEMBL21257385 | 0.86 | P2RY1 (0.64) | P2RY1P2RY2P2RY11NT5EENPP1 | |
| SCHEMBL21100457 | 0.84 | P2RY1 (0.65) | P2RY1P2RY2P2RY11NT5EENPP1 | |
| SCHEMBL21257356 | 0.83 | P2RY1 (0.63) | P2RY1P2RY2P2RY11ADORA1NT5E | |
| SCHEMBL26934764 | 0.81 | P2RY1 (0.70) | P2RY1P2RY2P2RY11ADORA1ENPP1 | |
| SCHEMBL23125573 | 0.81 | ADORA3 (0.61) | P2RY1ADORA1HSP90AA1ADORA3HSP90B1 | |
| SCHEMBL23125574 | 0.81 | ADORA3 (0.61) | P2RY1ADORA1HSP90AA1ADORA3HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3445368-B1 | COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | ASTROCYTE PHARMACEUTICALS INC (US) | 2024-07-17 | — | — | EP | disclosed |
| WO-2019157317-A1 | COMPOUNDS AND METHODS FOR TREATING ADDICTION AND RELATED DISORDERS | ASTROCYTE PHARMACEUTICALS, INC. (US) | 2019-08-15 | — | — | WO | disclosed |
| WO-2017185061-A1 | COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | ASTROCYTE PHARMACEUTICALS, INC. (US) | 2017-10-26 | — | — | WO | disclosed |