Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 9/20 | 0.57 |
| ▸ | P2RY11 | Q96G91 | 3/20 | 0.53 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.53 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.53 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.53 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.53 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.51 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.49 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19503941 | 0.88 | P2RY1 (0.68) | P2RY1P2RY11ENPP1P2RX1P2RX3 | |
| SCHEMBL25613500 | 0.87 | P2RY1 (0.52) | P2RY1P2RY11ENPP1P2RX1P2RX3 | |
| SCHEMBL19503942 | 0.87 | P2RY1 (0.67) | P2RY1P2RY11ENPP1P2RX1P2RX3 | |
| SCHEMBL21257359 | 0.83 | P2RY1 (0.59) | P2RY1P2RY11ENPP1P2RX1P2RX3 | |
| SCHEMBL19807533 | 0.82 | P2RY1 (0.58) | P2RY1P2RY11ENPP1P2RX1P2RX3 | |
| SCHEMBL19503346 | 0.78 | P2RY1 (0.56) | P2RY1P2RY11ENPP1P2RX1P2RX3 | |
| SCHEMBL19503349 | 0.77 | P2RY1 (0.67) | P2RY1 | |
| SCHEMBL19807534 | 0.77 | P2RY1 (0.79) | P2RY1P2RY11P2RY2 | |
| SCHEMBL19464929 | 0.77 | P2RY1 (0.68) | P2RY1P2RY11ENPP1P2RX1P2RX3 | |
| SCHEMBL19464930 | 0.76 | P2RY1 (0.68) | P2RY1P2RY11ENPP1P2RX1P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017185061-A1 | COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | ASTROCYTE PHARMACEUTICALS, INC. (US) | 2017-10-26 | — | — | WO | disclosed |