Oxindole

Oxindole

SCHEMBL19504

O=C1Cc2ccccc2N1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 5/20 1.00
PDK2 Q15119 1/20 1.00
NPC1 O15118 2/20 0.65
MAPK13 O15264 1/20 0.65
MAPK12 P53778 1/20 0.65
MAPK11 Q15759 1/20 0.65
MAPK14 Q16539 1/20 0.65
MAPT P10636 2/20 0.61
TDP2 O95551 1/20 0.57
CASP3 P42574 1/20 0.57
CASP7 P55210 1/20 0.57
CASP9 P55211 1/20 0.57
CASP6 P55212 1/20 0.57
CASP8 Q14790 1/20 0.57
MAP3K14 Q99558 1/20 0.57
KDM4E B2RXH2 1/20 0.56
MEN1 O00255 1/20 0.56
HSP90AA1 P07900 1/20 0.56
THRB P10828 1/20 0.56
HK1 P19367 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxindole SCHEMBL29358826 1.00 AHR (1.00) AHRPDK2NPC1MAPK13MAPK12
Oxindole SCHEMBL1144643 1.00 AHR (1.00) AHRPDK2NPC1MAPK13MAPK12
Oxindole SCHEMBL5624006 0.98 AHR (0.95) AHRPDK2NPC1MAPK13MAPK12
Oxindole SCHEMBL15636313 0.98 AHR (0.95) AHRPDK2NPC1MAPK13MAPK12
Oxindole SCHEMBL1236964 0.98 AHR (0.95) AHRPDK2NPC1MAPK13MAPK12
Oxindole SCHEMBL1462135 0.98 AHR (0.95) AHRPDK2NPC1MAPK13MAPK12
Oxindole SCHEMBL5502064 0.98 AHR (0.95) AHRPDK2NPC1MAPK13MAPK12
Oxindole SCHEMBL5668060 0.98 AHR (0.95) AHRPDK2NPC1MAPK13MAPK12
Oxindole SCHEMBL4720301 0.98 AHR (0.95) AHRPDK2NPC1MAPK13MAPK12
Oxindole SCHEMBL8866524 0.98 AHR (0.95) AHRPDK2NPC1MAPK13MAPK12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 18020 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637410-B2 Vesicular monoamine transporter-2 ligands and their use in the treatment of psychostimulant abuse UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2026-05-26 US claimed
EP-3841097-B1 2,6-BIS(((1H-BENZO[D]IMIDAZOL-2-YL)THIO)METHYL)PYRIDINE AND N2,N6-DIBENZYLPYRIDINE-2,6-DICARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS PHOSPHOINOSITIDE 3-KINASE (PI3K) INHIBITORS FOR TREATING CANCER BIOMEDICAL RES FOUNDATION OF THE ACADEMY OF ATHENS BRFAA (GR) 2026-05-20 EP claimed
US-20260103444-A1 8-HYDROXYQUINOLINE COMPOUND AND USE THEREOF UNIV OSAKA (JP) 2026-04-16 US claimed
EP-4720318-A1 METHODS AND COMPOSITIONS FOR THE PRODUCTION OF GLYOXAL Solugen, Inc. (US) 2026-04-08 EP claimed
EP-3768675-B1 NOVEL TRIAZOLONE DERIVATIVES OR SALTS THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME YUHAN CORP (KR) 2026-04-01 EP claimed
EP-4713096-A1 CDK INHIBITOR COMPOUNDS Aleksia Therapeutics, Inc. (US) 2026-03-25 EP claimed
US-12584924-B2 Compositions and methods for diagnosing and treating chronic kidney disease SOCIETE DES PRODUITS NESTLE S.A. (CH) 2026-03-24 US claimed
US-20260070896-A1 HETEROCYCLE DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS UNIV LEUVEN KATH (BE) 2026-03-12 US claimed
CN-121570460-A Application of oxindole compound in preparation of anti-vesicular stomatitis virus drugs 海南大学 2026-02-27 CN claimed
EP-4680215-A1 COMPOSITIONS AND METHODS FOR AMELIORATING ADVERSE EFFECTS OF THERAPIES MDX Management LLC (US) 2026-01-21 EP claimed
US-4145215-A PHOTOCONDUCTIVE PIGMENTS EASTMAN KODAK COMPANY (US) 1979-03-20 US claimed
US-4137331-A ANTIARRYTHMIA AGENTS SANDOZ LTD. (CH) 1979-01-30 US claimed
US-RE29882-E SALT FORMATION, REARRANGEMENT, DESULFURIZATION OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1979-01-16 US claimed
US-4127738-A Photovoltaic device containing an organic layer EXXON RESEARCH & ENGINEERING COMPANY (US) 1978-11-28 US claimed
US-4058607-A DIHALOVINYL DIALKYL PHOSPHATE, 1,3-BENZODIOXOLES AIRWICK INDUSTRIES, INC. (US) 1977-11-15 US claimed
US-4030932-A PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1977-06-21 US claimed
US-3972894-A Synthesis of oxindoles from anilines and β-thio carboxylic esters or amides THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1976-08-03 US claimed
US-3966900-A INSECTICIDES AIRWICK INDUSTRIES, INC. (US) 1976-06-29 US claimed
US-3965095-A Oxindole derivatives SANDOZ LTD. (CH) 1976-06-22 US claimed
US-3954797-A Process for preparing azasulfonium halide salts CHROMALLOY AMERICAN CORPORATION (US) 1976-05-04 US claimed