Oxindole

Oxindole

SCHEMBL29358826

O=C1Cc2ccccc2N1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 5/20 1.00
PDK2 Q15119 1/20 1.00
NPC1 O15118 2/20 0.65
MAPK13 O15264 1/20 0.65
MAPK12 P53778 1/20 0.65
MAPK11 Q15759 1/20 0.65
MAPK14 Q16539 1/20 0.65
MAPT P10636 2/20 0.61
TDP2 O95551 1/20 0.57
CASP3 P42574 1/20 0.57
CASP7 P55210 1/20 0.57
CASP9 P55211 1/20 0.57
CASP6 P55212 1/20 0.57
CASP8 Q14790 1/20 0.57
MAP3K14 Q99558 1/20 0.57
KDM4E B2RXH2 1/20 0.56
MEN1 O00255 1/20 0.56
HSP90AA1 P07900 1/20 0.56
THRB P10828 1/20 0.56
HK1 P19367 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxindole SCHEMBL19504 1.00 AHR (1.00) AHRPDK2NPC1MAPK13MAPK12
Oxindole SCHEMBL1144643 1.00 AHR (1.00) AHRPDK2NPC1MAPK13MAPK12
Oxindole SCHEMBL5624006 0.98 AHR (0.95) AHRPDK2NPC1MAPK13MAPK12
Oxindole SCHEMBL15636313 0.98 AHR (0.95) AHRPDK2NPC1MAPK13MAPK12
Oxindole SCHEMBL1236964 0.98 AHR (0.95) AHRPDK2NPC1MAPK13MAPK12
Oxindole SCHEMBL1462135 0.98 AHR (0.95) AHRPDK2NPC1MAPK13MAPK12
Oxindole SCHEMBL5502064 0.98 AHR (0.95) AHRPDK2NPC1MAPK13MAPK12
Oxindole SCHEMBL5668060 0.98 AHR (0.95) AHRPDK2NPC1MAPK13MAPK12
Oxindole SCHEMBL4720301 0.98 AHR (0.95) AHRPDK2NPC1MAPK13MAPK12
Oxindole SCHEMBL8866524 0.98 AHR (0.95) AHRPDK2NPC1MAPK13MAPK12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026104681-A1 NEW SULFONAMIDE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2026-05-21 WO claimed
US-12509366-B1 Nanocomposite for water decontamination IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY (SA) 2025-12-30 US claimed
EP-3846788-B1 PDE11 INHIBITORS FOR USE FOR THE TREATMENT OF PARKINSON'S DISEASE UNIV AMSTERDAM (NL) 2025-10-29 EP claimed
EP-4611899-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE Petra Pharma Corporation (US) 2025-09-10 EP claimed
US-12351484-B1 Water decontamination using nanocomposite IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY (SA) 2025-07-08 US claimed
US-12351485-B1 Nanocomposite for water decontamination IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY (SA) 2025-07-08 US claimed
US-20250145792-A1 POLYMER COMPOSITIONS HAVING DENSIFICATION ACCELERATORS AND ROTATIONAL MOLDING PROCESSES FOR MAKING HOLLOW ARTICLES THEREFROM CYTEC INDUSTRIES INC. (US) 2025-05-08 US claimed
CN-119876280-A New application of Pediococcus pentosaceus and preparation method of indigo naturalis 成都中医药大学 2025-04-25 CN claimed
EP-2563869-B3 UV-CURABLE ACRYLATE BASED INK, A PROCESS AND AN INK BASE FOR ITS PRODUCTION HAPA AG (CH) 2025-04-16 EP claimed
WO-2025075499-A1 REDUCING DOPAMINE FEED-BACK INHIBITION IN DOPAMINERGIC CELLS BY TADALAFIL. UNIVERSITEIT VAN AMSTERDAM (NL) 2025-04-10 WO claimed
WO-2022073135-A1 ORGANIC MOLECULE LIGHT EMITTERS THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2022-04-14 WO claimed
EP-3981809-A2 RESIN, RESIN COMPOSITION, AND DISPLAY DEVICE USING SAME Duksan Neolux Co., Ltd (KR) 2022-04-13 EP claimed
WO-2022070946-A1 PHOTOSENSITIVE RESIN COMPOSITION, CURED PRODUCT, DISPLAY DEVICE, AND METHOD FOR PRODUCING CURED PRODUCT 東レ株式会社 2022-04-07 WO claimed
US-20220106477-A1 RESIN, RESIN COMPOSITION, AND DISPLAY DEVICE USING SAME DUK SAN NEOLUX CO., LTD. (KR) 2022-04-07 US claimed
CN-114272243-A Indolinone compound and application thereof in myocardial injury 南京景瑞康分子医药科技有限公司 2022-04-05 CN claimed
CN-111662226-B 2-oxo-1, 2-dihydrobenzo [ cd ] indole compound 中国科学院广州生物医药与健康研究院 2022-03-18 CN claimed
CN-114149769-A High-reflection black adhesive film and preparation method and application thereof 苏州赛伍应用技术股份有限公司 2022-03-08 CN claimed
CN-112980353-B Black high-reflection high-thermal-conductivity PID-resistant EVA (ethylene vinyl acetate) packaging adhesive film and preparation method and application thereof 江苏鹿山新材料有限公司 2022-03-04 CN claimed
CN-113999214-A Indole dihydrofuran ring derivative and preparation method and application thereof 中山大学 2022-02-01 CN claimed
WO-2022017444-A1 SHP2 INHIBITOR AND COMPOSITION AND APPLICATION THEREOF 贝达药业股份有限公司 2022-01-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509366-B1 Nanocomposite for water decontamination BET1, SCO2, PYM1 AHR 3578/4885PDK2 4559/4885NPC1 633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.