⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23309187 | 0.84 | MMP9 (0.36) | — | |
| SCHEMBL23309114 | 0.70 | MMP9 (0.39) | — | |
| SCHEMBL22098279 | 0.65 | — | — | |
| SCHEMBL10035000 | 0.65 | MMP9 (0.38) | — | |
| SCHEMBL23309085 | 0.64 | MMP9 (0.49) | — | |
| SCHEMBL23309143 | 0.63 | MMP9 (0.39) | — | |
| SCHEMBL13937965 | 0.62 | MMP9 (0.38) | — | |
| SCHEMBL23964614 | 0.62 | RAD52 (0.44) | — | |
| SCHEMBL13937972 | 0.62 | PIK3R1 (0.33) | — | |
| SCHEMBL15946750 | 0.61 | DPP4 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11365192-B2 | Pyridine compound substituted with azole | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2022-06-21 | — | — | US | disclosed |
| US-20210122741-A1 | PYRIDINE COMPOUND SUBSTITUTED WITH AZOLE | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2021-04-29 | — | — | US | disclosed |
| US-20170305922-A1 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-10-26 | — | — | US | disclosed |