Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19505771 | 0.97 | TSHR (0.52) | TSHRMEN1KMT2ATP53CNR1 | |
| SCHEMBL19475012 | 0.90 | MEN1 (0.58) | TSHRMEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL19475014 | 0.90 | MEN1 (0.58) | TSHRMEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL19475145 | 0.86 | MEN1 (0.53) | TSHRMEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL19475146 | 0.86 | MEN1 (0.53) | TSHRMEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL10724171 | 0.85 | CNR1 (0.53) | TSHRMEN1KMT2ACNR1CNR2 | |
| SCHEMBL20366927 | 0.82 | TP53 (0.54) | TSHRMEN1KMT2ATP53CNR1 | |
| SCHEMBL13469107 | 0.81 | CNR1 (0.50) | TSHRMEN1KMT2ACNR1CNR2 | |
| SCHEMBL15614466 | 0.79 | KMT2A (0.52) | TSHRMEN1KMT2ACNR1CNR2 | |
| SCHEMBL19505782 | 0.78 | CNR2 (0.50) | TSHRMEN1KMT2ACNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017184558-A1 | NOVEL PROMYSALIN ANALOGUES AND METHODS OF USE THEREOF | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2017-10-26 | — | — | WO | disclosed |