Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GYS1 | P13807 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19475145 | 1.00 | MEN1 (0.53) | MEN1TSHRKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL19475012 | 0.96 | MEN1 (0.58) | MEN1TSHRKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL19475014 | 0.96 | MEN1 (0.58) | MEN1TSHRKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL19505771 | 0.89 | TSHR (0.52) | MEN1TSHRKMT2AALDH1A1TP53 | |
| SCHEMBL19505982 | 0.86 | TSHR (0.57) | MEN1TSHRKMT2AALDH1A1TP53 | |
| SCHEMBL3855387 | 0.81 | ALDH1A1 (0.54) | MEN1TSHRKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL11640739 | 0.81 | ALDH1A1 (0.54) | MEN1TSHRKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7393837 | 0.81 | ALDH1A1 (0.60) | MEN1TSHRKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL15743802 | 0.78 | MEN1 (0.68) | MEN1TSHRKMT2AALDH1A1NPSR1 | |
| SCHEMBL20858858 | 0.78 | ITGB1 (0.67) | KMT2AALDH1A1L3MBTL1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017184558-A1 | NOVEL PROMYSALIN ANALOGUES AND METHODS OF USE THEREOF | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2017-10-26 | — | — | WO | disclosed |