Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | FFAR2 | O15552 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19506182 | 0.85 | KMT2A (0.36) | HSD11B1KMT2ALMNATSHRALDH1A1 | |
| SCHEMBL19475410 | 0.78 | ITGB1 (0.45) | ITGB1ITGA5KMT2ALMNATSHR | |
| SCHEMBL19506177 | 0.77 | TSHR (0.38) | HSD11B1KMT2ALMNATSHRALDH1A1 | |
| SCHEMBL19505798 | 0.76 | KMT2A (0.37) | HSD11B1KMT2ALMNATSHRALDH1A1 | |
| SCHEMBL19475313 | 0.74 | KDM4E (0.36) | ITGB1ITGA5KMT2ALMNATSHR | |
| SCHEMBL19475315 | 0.74 | KDM4E (0.36) | ITGB1ITGA5KMT2ALMNATSHR | |
| SCHEMBL19506085 | 0.73 | ALDH1A1 (0.35) | HSD11B1KMT2ALMNATSHRALDH1A1 | |
| SCHEMBL19506202 | 0.73 | KMT2A (0.38) | HSD11B1KMT2ALMNATSHRALDH1A1 | |
| SCHEMBL19505793 | 0.71 | TSHR (0.38) | HSD11B1KMT2ALMNATSHRALDH1A1 | |
| SCHEMBL19505782 | 0.66 | CNR2 (0.50) | KMT2ATSHRALDH1A1HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017184558-A1 | NOVEL PROMYSALIN ANALOGUES AND METHODS OF USE THEREOF | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2017-10-26 | — | — | WO | disclosed |