Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.77 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12580668 | 0.88 | PTGDR2 (0.76) | PTGDR2TBXAS1 | |
| SCHEMBL1598755 | 0.87 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL1599386 | 0.86 | PTGDR2 (0.81) | PTGDR2 | |
| SCHEMBL1466910 | 0.83 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL12580666 | 0.83 | PTGDR2 (0.77) | PTGDR2 | |
| SCHEMBL27799169 | 0.83 | PTGDR2 (0.76) | PTGDR2TBXAS1 | |
| SCHEMBL1466225 | 0.82 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL1599841 | 0.82 | PTGDR2 (0.82) | PTGDR2 | |
| SCHEMBL1599801 | 0.81 | PTGDR2 (0.82) | PTGDR2 | |
| SCHEMBL19506937 | 0.81 | PTGDR2 (0.52) | PTGDR2TBXAS1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828359-B2 | Process for the preparation of 3-substituted (indol-1-yl)-acetic acid esters | ATOPIX THERAPEUTICS LIMITED (GB) | 2017-11-28 | — | — | US | disclosed |
| US-20170305879-A1 | PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED (INDOL-1-YL)-ACETIC ACID ESTERS | ZACH SYSTEM SPA (IT) | 2017-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170305879-A1 | PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED (INDOL-1-YL)-ACETIC ACID ESTERS | IDO1, IDO2, SI | PTGDR2 1790/4885TBXAS1 1379/4885POLB 4045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.