SCHEMBL19508294

SCHEMBL19508294

Cc1ccc(-c2ccccc2C)[nH]1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMBS P08397 1/20 0.43
HPGD P15428 4/20 0.43
RAB9A P51151 4/20 0.43
SMN1; SMN2 Q16637 4/20 0.43
ALOX15 P16050 3/20 0.43
TSHR P16473 2/20 0.43
USP2 O75604 2/20 0.43
MAPT P10636 2/20 0.43
GAA P10253 2/20 0.43
NFKB1 P19838 1/20 0.43
NFKB2 Q00653 1/20 0.43
RELA Q04206 1/20 0.43
NPC1 O15118 3/20 0.40
NPSR1 Q6W5P4 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
NPY5R Q15761 1/20 0.40
LMNA P02545 1/20 0.40
TP53 P04637 1/20 0.40
GLA P06280 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8962876 0.78 IDO1 (0.47) HMBSHPGDRAB9ASMN1; SMN2ALOX15
SCHEMBL17266876 0.75 KDM4E (0.44) HPGDRAB9ASMN1; SMN2ALOX15TSHR
SCHEMBL12141823 0.74 HMBS (0.67) HMBS
SCHEMBL31747856 0.74 CYP19A1 (0.43) HPGDRAB9ASMN1; SMN2ALOX15TSHR
SCHEMBL21686600 0.72 HPGD (0.54) HPGDRAB9ASMN1; SMN2ALOX15TSHR
SCHEMBL1104622 0.72 HMBS (0.62) HMBS
SCHEMBL12000745 0.72 HMBS (0.62) HMBS
SCHEMBL15788744 0.72 HMBS (0.62) HMBS
SCHEMBL10054604 0.72 HMBS (0.62) HMBS
SCHEMBL1450720 0.71 HMBS (0.48) HMBSHPGDRAB9ASMN1; SMN2USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017191896-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-11-09 WO disclosed
WO-2017188672-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-11-02 WO disclosed
WO-2017183859-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-10-26 WO disclosed