Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 9/20 | 0.67 |
| ▸ | GRM3 | Q14832 | 9/20 | 0.67 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20722216 | 0.80 | GRM2 (1.00) | GRM2GRM3 | |
| SCHEMBL23699449 | 0.80 | GRM2 (1.00) | GRM2GRM3 | |
| SCHEMBL20730930 | 0.80 | GRM2 (1.00) | GRM2GRM3 | |
| SCHEMBL22130893 | 0.80 | GRM2 (0.80) | GRM2GRM3 | |
| SCHEMBL22130892 | 0.78 | GRM2 (0.74) | GRM2GRM3 | |
| SCHEMBL19508605 | 0.68 | GRM2 (0.78) | GRM2GRM3 | |
| SCHEMBL19508606 | 0.68 | GRM2 (0.78) | GRM2GRM3 | |
| SCHEMBL31381231 | 0.66 | GRM2 (0.52) | GRM2GRM3DRD4TMEM97SIGMAR1 | |
| SCHEMBL8764439 | 0.66 | GRM2 (0.81) | GRM2GRM3 | |
| SCHEMBL20309287 | 0.65 | GRM2 (0.55) | GRM2GRM3SIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017183734-A1 | PRODRUG OF AMINO ACID DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2017-10-26 | — | — | WO | disclosed |