Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MOK | Q9UQ07 | 5/20 | 0.82 |
| ▸ | PLAUR | Q03405 | 9/20 | 0.66 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19475473 | 0.90 | MOK (1.00) | MOKPLAURTRPV1ALDH1A1TSHR | |
| SCHEMBL19508991 | 0.89 | MOK (0.85) | MOKPLAURTRPV1ALDH1A1TSHR | |
| SCHEMBL19475479 | 0.87 | MOK (0.74) | MOKPLAURTRPV1ALDH1A1TSHR | |
| SCHEMBL19475307 | 0.82 | MOK (0.73) | MOKPLAURALDH1A1TSHRKDM4E | |
| SCHEMBL19475491 | 0.82 | MOK (1.00) | MOKPLAURTRPV1ALDH1A1TSHR | |
| SCHEMBL19475292 | 0.81 | MOK (1.00) | MOKPLAURTRPV1ALDH1A1USP2 | |
| SCHEMBL19475304 | 0.77 | MOK (0.73) | MOKPLAURTRPV1ALDH1A1TSHR | |
| SCHEMBL19475493 | 0.74 | MOK (1.00) | MOKTRPV1ALDH1A1TSHRKDM4E | |
| SCHEMBL19475475 | 0.72 | MOK (1.00) | MOKTRPV1ALDH1A1TSHRKDM4E | |
| SCHEMBL10760683 | 0.72 | ALDH1A1 (1.00) | MOKPLAURTRPV1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017184547-A1 | QUINOLINE COMPOUNDS AS MODULATORS OF RAGE ACTIVITY AND USES THEREOF | NEW YORK UNIVERSITY (US) | 2017-10-26 | — | — | WO | disclosed |