SCHEMBL19508729

SCHEMBL19508729

CC(C)(C)OC(=O)/N=C(/NC(=O)OC(C)(C)C)Nc1ccc(OC(=O)C2(C)COC(=O)OC2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPE Q05469 2/20 0.34
PSMB8 P28062 1/20 0.34
TDP2 O95551 1/20 0.33
NR1H4 Q96RI1 1/20 0.32
PRKDC P78527 1/20 0.32
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
BRD4 O60885 1/20 0.31
CREBBP Q92793 1/20 0.31
PPARG P37231 1/20 0.31
PPARA Q07869 1/20 0.31
POLB P06746 1/20 0.31
CYP17A1 P05093 2/20 0.31
KDM1A O60341 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18256739 1.00 LIPE (0.34) LIPEPSMB8TDP2NR1H4PRKDC
SCHEMBL18256760 0.87 CA1 (0.39) NR1H4KDM4ENPC1ALDH1A1LMNA
SCHEMBL18257739 0.87 CA1 (0.39) NR1H4KDM4ENPC1ALDH1A1LMNA
SCHEMBL18257757 0.84 LIPE (0.36) LIPEPSMB8TDP2PRKDCKDM4E
SCHEMBL19508958 0.82 LIPE (0.37) LIPEPSMB8TDP2NR1H4PRKDC
SCHEMBL20982174 0.79 GAA (0.31)
SCHEMBL10092627 0.76 CYP17A1 (0.48) PSMB8NR1H4PRKDCSMN1; SMN2BRD4
SCHEMBL14155353 0.76 CYP17A1 (0.48) PSMB8NR1H4PRKDCSMN1; SMN2BRD4
SCHEMBL18257736 0.76 IDO1 (0.32) CA12CA1CA9
SCHEMBL12629708 0.76 IDO1 (0.32) CA12CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11690380-B2 Antimicrobial guanidinium and thiouronium functionalized polymers CORAL BAY II, LLC (US) 2023-07-04 US disclosed
US-10980234-B2 Antimicrobial guanidinium and thiouronium functionalized polymers CORAL BAY II, LLC (US) 2021-04-20 US disclosed
US-10779539-B2 Antimicrobial guanidinium and thiouronium functionalized polymers CORAL BAY II, LLC. (US) 2020-09-22 US disclosed
US-20170303541-A1 ANTIMICROBIAL GUANIDINIUM AND THIOURONIUM FUNCTIONALIZED POLYMERS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2017-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170303541-A1 ANTIMICROBIAL GUANIDINIUM AND THIOURONIUM FUNCTIONALIZED POLYMERS PUF60, CAPG, GMPS LIPE 4083/4885PSMB8 2295/4885TDP2 1797/4885
US-10980234-B2 Antimicrobial guanidinium and thiouronium functionalized polymers PUF60, CAPG, GMPS LIPE 4083/4885PSMB8 2295/4885TDP2 1797/4885
US-11690380-B2 Antimicrobial guanidinium and thiouronium functionalized polymers PUF60, CAPG, GMPS LIPE 4083/4885PSMB8 2295/4885TDP2 1797/4885
US-10779539-B2 Antimicrobial guanidinium and thiouronium functionalized polymers PUF60, CAPG, GMPS LIPE 4083/4885PSMB8 2295/4885TDP2 1797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.