Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN3 | Q9UGI6 | 6/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.36 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.35 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1934675 | 0.88 | KCNN3 (0.34) | KCNN3PDE10AOPRM1P2RX7 | |
| SCHEMBL14158398 | 0.74 | PDE10A (0.48) | KCNN3PDE10AKCNN1KCNN2CCNT1 | |
| SCHEMBL12587700 | 0.74 | PDE10A (0.43) | KCNN3PDE10AKCNN1KCNN2MEN1 | |
| SCHEMBL2033397 | 0.73 | KCNN3 (0.52) | KCNN3PDE10AKCNN1KCNN2CCNT1 | |
| SCHEMBL14158263 | 0.72 | PDE10A (0.51) | KCNN3PDE10AKCNN1KCNN2MEN1 | |
| SCHEMBL4213434 | 0.71 | PDE10A (0.45) | KCNN3PDE10AKCNN1KCNN2P2RX7 | |
| SCHEMBL19512332 | 0.69 | AKT1 (0.31) | OPRM1 | |
| SCHEMBL14242902 | 0.66 | PDE10A (0.61) | KCNN3PDE10AKCNN1KCNN2 | |
| SCHEMBL13117303 | 0.65 | PDE10A (0.38) | KCNN3PDE10AKCNN1KCNN2 | |
| SCHEMBL13263839 | 0.65 | PDE10A (0.54) | KCNN3PDE10AKCNN1KCNN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509602-B9 | PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS | SENHWA BIOSCIENCES INC (TW) | 2017-11-01 | — | — | EP | disclosed |