Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | PPM1A | P35813 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL129156 | 0.89 | MAPT (0.52) | CYP3A4MAPTHPGDKDM4EALDH1A1 | |
| SCHEMBL14930684 | 0.86 | CYP3A4 (0.49) | CYP3A4MAPTHPGDKDM4EALDH1A1 | |
| SCHEMBL198013 | 0.86 | CYP3A4 (0.51) | CYP3A4MAPTHPGDKDM4EALDH1A1 | |
| SCHEMBL179695 | 0.83 | CYP3A4 (0.53) | CYP3A4MAPTHPGDKDM4EALDH1A1 | |
| SCHEMBL128098 | 0.81 | CYP3A4 (0.47) | CYP3A4MAPTHPGDKDM4EALDH1A1 | |
| SCHEMBL127939 | 0.81 | CYP3A4 (0.43) | CYP3A4MAPTHPGDKDM4EALDH1A1 | |
| SCHEMBL195229 | 0.78 | ALDH1A1 (0.49) | CYP3A4MAPTHPGDKDM4EALDH1A1 | |
| SCHEMBL127933 | 0.78 | CYP3A4 (0.45) | CYP3A4MAPTHPGDKDM4EALDH1A1 | |
| SCHEMBL193612 | 0.75 | MAPT (0.52) | CYP3A4MAPTHPGDKDM4EALDH1A1 | |
| SCHEMBL129004 | 0.74 | CYP3A4 (0.47) | CYP3A4MAPTHPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120059026-A1 | ANTIMICROBIAL AGENTS | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059026-A1 | ANTIMICROBIAL AGENTS | ZYX, Q6ZSR9, ZC3HAV1L | CYP3A4 464/4885MAPT 4740/4885HPGD 4046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.