Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 3/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30873963 | 0.84 | NPSR1 (0.53) | PTGER4PTGER3PTGER2PTGER1FFAR1 | |
| SCHEMBL1030914 | 0.84 | NPSR1 (0.53) | PTGER4PTGER3PTGER2PTGER1FFAR1 | |
| SCHEMBL4322411 | 0.82 | CES2 (0.42) | IAPPALDH1A1FFAR4MPOKDM4E | |
| SCHEMBL4601007 | 0.82 | TAAR1 (0.50) | ALDH1A1NPSR1CYP4F2CYP4A11NOTUM | |
| SCHEMBL12955273 | 0.80 | CYP4F2 (0.43) | ALDH1A1CYP4F2CYP4A11KDM4EHSD17B10 | |
| SCHEMBL17605475 | 0.79 | IAPP (0.34) | IAPPPTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL14128655 | 0.78 | PTGER1 (0.47) | PTGER4PTGER3PTGER2PTGER1FFAR1 | |
| SCHEMBL16958402 | 0.76 | TAAR1 (0.38) | ALDH1A1MPOHPGDHSD17B10 | |
| SCHEMBL2527059 | 0.74 | TAAR1 (0.52) | ALDH1A1FFAR1FFAR4MPOMEN1 | |
| SCHEMBL30799043 | 0.74 | TAAR1 (0.52) | ALDH1A1FFAR1FFAR4MPOMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017184549-A1 | PYRROLOPYRIDINE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF | INNOV17 LLC (US) | 2017-10-26 | — | — | WO | disclosed |