SCHEMBL19520

SCHEMBL19520

ClCOCc1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.70
IDO1 P14902 1/20 0.50
AGXT P21549 1/20 0.48
ALDH1A1 P00352 1/20 0.46
CA1 P00915 5/20 0.45
CA2 P00918 3/20 0.45
CA9 Q16790 3/20 0.45
CA7 P43166 2/20 0.45
KDM4E B2RXH2 1/20 0.45
POLB P06746 1/20 0.45
TACR1 P25103 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30397113 0.97 TSHR (0.67) TSHRIDO1AGXTALDH1A1CA1
Phosphine SCHEMBL7705717 0.97 TSHR (0.67) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL10660158 0.97 TSHR (0.67) TSHRIDO1AGXTALDH1A1CA1
Hydrochloric Acid SCHEMBL28406455 0.95 TSHR (0.64) TSHRIDO1AGXTALDH1A1CA1
Magnesium Chloride Anhydrous SCHEMBL28406453 0.93 TSHR (0.61) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL344059 0.88 TSHR (0.61) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL71046 0.88 TSHR (0.61) TSHRIDO1AGXTALDH1A1CA1
Methylene Chloride SCHEMBL27690292 0.86 TSHR (0.83) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL14947971 0.86 TSHR (0.48) TSHRIDO1AGXTALDH1A1CA2
SCHEMBL25310046 0.84 TSHR (0.56) TSHRIDO1AGXTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3682 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122079847-A Key intermediate of 3-hydroxymethyl azetidine-1-carboxylic acid tert-butyl ester and preparation method thereof 2026-05-26 CN claimed
CN-119638697-A ERVITSINE total synthesis method 南方科技大学 2025-03-18 CN claimed
CN-119528820-A Apricoxiyet Synthesis method of tam 浙江国邦药业有限公司 2025-02-28 CN claimed
CN-118807509-A Modified polysulfone membrane and preparation method thereof 清华大学 2024-10-22 CN claimed
US-20240279225-A1 COMPOUNDS AND METHODS FOR THERANOSTIC TARGETING OF PARP ACTIVITY BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-08-22 US claimed
CN-118348192-A Method for detecting total chlorine of benzyl chloromethyl ether 江西亚太科技发展有限公司 2024-07-16 CN claimed
CN-113024359-B Process for preparing alkoxymethyl alkynyl ether compounds having terminal triple bonds 信越化学工业株式会社 2024-06-11 CN claimed
CN-118063409-A Preparation method of cefdinir and intermediate thereof 江苏美迪克化学品有限公司 2024-05-24 CN claimed
CN-117976970-A Electrolyte, battery monomer, preparation method of battery monomer, battery and power utilization device 宁德时代新能源科技股份有限公司 2024-05-03 CN claimed
WO-2024087799-A1 ELECTROLYTE, BATTERY CELL AND PREPARATION METHOD THEREFOR, BATTERY, AND ELECTRIC DEVICE 宁德时代新能源科技股份有限公司 2024-05-02 WO claimed
US-6566553-B2 Synthetic pathway relies upon stereospecific synthesis of oxazoline intermediate and stereoselective addition of formyl amide to oxazoline MILLENNIUM PHARMACEUTICALS, INC. 2003-05-20 US claimed
US-20020016355-A1 Synthesis of clasto-lactacystin beta-lactone and analogs thereof SOUCY FRANCOIS (US) 2002-02-07 US claimed
CN-1321632-A (4S,5S)-and (4R,5R)-gamma-methyl-delta-hydroxyl-alkanoic acid and its alkyl ester, preparation method and application SHANGHAI INST ORGANIC CHEM (CN) 2001-11-14 CN claimed
EP-1021407-A4 SYNTHESIS OF CLASTO-LACTACYSTIN BETA-LACTONE AND ANALOGS THEREOF MILLENNIUM PHARM INC (US) 2001-07-04 EP claimed
CN-1271342-A Synthesis of clasto-lactacystin-beta-lactone and analogs thereof SOUCY F (US) 2000-10-25 CN claimed
EP-1021407-A1 SYNTHESIS OF CLASTO-LACTACYSTIN BETA-LACTONE AND ANALOGS THEREOF Millennium Pharmaceuticals, Inc. (US) 2000-07-26 EP claimed
WO-1999009006-A1 SYNTHESIS OF CLASTO-LACTACYSTIN β-LACTONE AND ANALOGS THEREOF SOUCY FRANCOIS (US) 1999-02-25 WO claimed
WO-1998046577-A1 NOVEL OXAZOLIDINONES AND METHODS FOR THE SYNTHESIS AND USE OF SAME THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1998-10-22 WO claimed
EP-0377031-A1 5-DEAZA-5,7-DISUBSTITUTED-AMINOPTERIN ANALOGUES Sloan-Kettering Institute For Cancer Research (US) 1990-07-11 EP claimed
WO-1990000172-A1 5-DEAZA-5,7-DISUBSTITUTED-AMINOPTERIN ANALOGUES SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1990-01-11 WO claimed