Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.53 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.53 |
| ▸ | TNKS | O95271 | 1/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19520280 | 1.00 | TDP1 (0.60) | TDP1GLAALDH1A1HDAC3HDAC4 | |
| SCHEMBL5598795 | 0.90 | TDP1 (0.61) | TDP1GLAALDH1A1HDAC3HDAC4 | |
| SCHEMBL5598797 | 0.90 | TDP1 (0.61) | TDP1GLAALDH1A1HDAC3HDAC4 | |
| SCHEMBL10349072 | 0.87 | TDP1 (0.57) | TDP1GLAALDH1A1HDAC3HDAC4 | |
| SCHEMBL2622483 | 0.82 | TDP1 (0.61) | TDP1GLAALDH1A1HDAC3HDAC4 | |
| SCHEMBL5231718 | 0.82 | TDP1 (0.61) | TDP1GLAALDH1A1HDAC3HDAC4 | |
| SCHEMBL27727863 | 0.81 | TDP1 (0.59) | TDP1GLAALDH1A1HDAC3HDAC4 | |
| SCHEMBL7177472 | 0.80 | MAPT (0.61) | TDP1GLAALDH1A1HDAC3HDAC4 | |
| SCHEMBL21878949 | 0.80 | MAPT (0.61) | TDP1GLAALDH1A1HDAC3HDAC4 | |
| SCHEMBL7050399 | 0.80 | MAPT (0.61) | TDP1GLAALDH1A1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3448843-B1 | ARYL BETA DIKETONES AND THEIR USE A ODORANTS | GIVAUDAN SA (CH) | 2021-02-24 | — | — | EP | claimed |
| US-10577298-B2 | Aryl beta diketones and their use as odorants | GIVAUDAN S.A. (CH) | 2020-03-03 | — | — | US | claimed |
| US-20190127305-A1 | ARYL BETA DIKETONES AND THEIR USE AS ODORANTS | GIVAUDAN SA (CH) | 2019-05-02 | — | — | US | claimed |
| WO-2017186846-A1 | ARYL BETA DIKETONES AND THEIR USE A ODORANTS | GIVAUDAN SA (CH) | 2017-11-02 | — | — | WO | claimed |
| EP-3448843-B1 | ARYL BETA DIKETONES AND THEIR USE A ODORANTS | GIVAUDAN SA (CH) | 2021-02-24 | — | — | EP | disclosed |
| US-10577298-B2 | Aryl beta diketones and their use as odorants | GIVAUDAN S.A. (CH) | 2020-03-03 | — | — | US | disclosed |
| US-20190127305-A1 | ARYL BETA DIKETONES AND THEIR USE AS ODORANTS | GIVAUDAN SA (CH) | 2019-05-02 | — | — | US | disclosed |
| WO-2017186846-A1 | ARYL BETA DIKETONES AND THEIR USE A ODORANTS | GIVAUDAN SA (CH) | 2017-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10577298-B2 | Aryl beta diketones and their use as odorants | CBR3, CBR1, CHRM3 | TDP1 4115/4885GLA 2980/4885ALDH1A1 941/4885 |
| US-20190127305-A1 | ARYL BETA DIKETONES AND THEIR USE AS ODORANTS | CBR3, CBR1, CHRM3 | TDP1 4115/4885GLA 2980/4885ALDH1A1 941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.