Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | TACR2 | P21452 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6785369 | 0.92 | MAPT (0.36) | TYRMAPTHTTKDM4EALDH1A1 | |
| SCHEMBL3918783 | 0.74 | TYR (0.37) | TYRALOX5TP53CYP3A4PTGS2 | |
| SCHEMBL3922014 | 0.74 | TYR (0.37) | TYRALOX5TP53CYP3A4PTGS2 | |
| SCHEMBL3920357 | 0.72 | TYR (0.34) | TYRTP53CYP3A4MAPTTSHR | |
| SCHEMBL16701741 | 0.72 | TYR (0.42) | TYRLIPGALOX5TP53CYP3A4 | |
| SCHEMBL2964011 | 0.71 | HTT (0.38) | TYRLIPGALOX5TP53CYP3A4 | |
| SCHEMBL2969617 | 0.71 | MAPT (0.35) | TYRMAPTHTTALDH1A1 | |
| SCHEMBL28522920 | 0.71 | LIPG (0.43) | TYRLIPGALOX5TP53CYP3A4 | |
| SCHEMBL14389463 | 0.71 | MAPT (0.35) | MAPTHTTALDH1A1 | |
| SCHEMBL11781337 | 0.71 | TYR (0.36) | TYRALOX5TP53CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017189865-A1 | LIPIDIC FURAN, PYRROLE, AND THIOPHENE COMPOUNDS FOR USE IN THE TREATMENT OF ATROPHIC VAGINITIS | AVOSCIENCE, LLC (US) | 2017-11-02 | — | — | WO | disclosed |