SCHEMBL195216

SCHEMBL195216

O=C1OC(=O)c2c(Br)c(Br)c(Br)c(Cl)c21

nearest known ligand 0.71

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.71
ALDH1A1 P00352 1/20 0.56
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9672390 0.93 TSHR (0.65) TSHRALDH1A1
SCHEMBL10397991 0.91 TSHR (0.64) TSHRALDH1A1
SCHEMBL195217 0.88 TSHR (0.67) TSHRALDH1A1CA1CA2CA4
SCHEMBL29376586 0.84 TSHR (1.00) TSHRALDH1A1CA1CA2CA4
SCHEMBL194752 0.84 TSHR (1.00) TSHRALDH1A1CA1CA2CA4
SCHEMBL9671421 0.83 TSHR (0.67) TSHRALDH1A1
SCHEMBL30361965 0.82 TSHR (0.65) TSHRALDH1A1
SCHEMBL9822841 0.82 TSHR (0.65) TSHRALDH1A1
Ammonia Solution, Strong SCHEMBL7773774 0.82 TSHR (0.94) TSHRALDH1A1CA1CA2CA4
SCHEMBL10397261 0.81 TSHR (0.71) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1717277-B1 Pixel-forming colorant compositions and their use DAINICHISEIKA COLOR CHEM (JP) 2012-01-04 EP disclosed
US-7611572-B2 Pixel-forming colorant compositions and their use DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2009-11-03 US disclosed
EP-1717277-A2 Pixel-forming colorant compositions and their use Dainichiseika Color & Chemicals Mfg. Co., Ltd. (JP) 2006-11-02 EP disclosed
US-20060213394-A1 PIXEL-FORMING COLORANT COMPOSITIONS AND THEIR USE DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2006-09-28 US disclosed
US-4978699-A Reaction product of hindered amine with primary amine or reactive hydrazide group and halogenated cyclic anhydride; for extrusion with polymers ATOCHEM NORTH AMERICA, INC. (US) 1990-12-18 US disclosed
EP-0366057-A2 Light stabilizing flame retardants ATOCHEM NORTH AMERICA, INC. (a Pennsylvania corp.) (US) 1990-05-02 EP disclosed