Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30361965 | 0.93 | TSHR (0.65) | TSHRALDH1A1 | |
| SCHEMBL9822841 | 0.93 | TSHR (0.65) | TSHRALDH1A1 | |
| SCHEMBL10397991 | 0.91 | TSHR (0.64) | TSHRALDH1A1 | |
| SCHEMBL9671421 | 0.88 | TSHR (0.67) | TSHRALDH1A1CYP3A4THRBHPGD | |
| SCHEMBL21861 | 0.84 | TSHR (1.00) | TSHRALDH1A1UCHL1UCHL3ECE1 | |
| SCHEMBL30354042 | 0.84 | TSHR (1.00) | TSHRALDH1A1UCHL1UCHL3ECE1 | |
| SCHEMBL195217 | 0.83 | TSHR (0.67) | TSHRALDH1A1 | |
| SCHEMBL9672390 | 0.82 | TSHR (0.65) | TSHRALDH1A1 | |
| Water SCHEMBL28019026 | 0.82 | TSHR (0.94) | TSHRALDH1A1UCHL1UCHL3ECE1 | |
| SCHEMBL195216 | 0.81 | TSHR (0.71) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4978699-A | Reaction product of hindered amine with primary amine or reactive hydrazide group and halogenated cyclic anhydride; for extrusion with polymers | ATOCHEM NORTH AMERICA, INC. (US) | 1990-12-18 | — | — | US | disclosed |
| EP-0366057-A2 | Light stabilizing flame retardants | ATOCHEM NORTH AMERICA, INC. (a Pennsylvania corp.) (US) | 1990-05-02 | — | — | EP | disclosed |