Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.65 |
| ▸ | MAOB | P27338 | 5/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.65 |
| ▸ | SDHA | P31040 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | CALML3 | P27482 | 1/20 | 0.65 |
| ▸ | F10 | P00742 | 7/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1949023 | 1.00 | MAOA (0.65) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL1951688 | 1.00 | MAOA (0.65) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL1949024 | 1.00 | MAOA (0.65) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL4166298 | 0.96 | MAOB (0.68) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL4163736 | 0.90 | MAOA (0.61) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL4163743 | 0.90 | MAOA (0.61) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL4176691 | 0.90 | MAOA (0.62) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL13944748 | 0.90 | MAOA (0.62) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL4176687 | 0.90 | MAOA (0.62) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL1949701 | 0.89 | MAOA (0.66) | MAOAMAOBPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2324016-B1 | 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | FERRER INT (ES) | 2012-04-25 | — | — | EP | claimed |
| US-20110136829-A1 | 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | FERRER INTERNACIONAL, S.A. (ES) | 2011-06-09 | — | — | US | claimed |
| EP-2141162-A1 | 3-(n-heterocyclyl)-pyrrolidinyl-phenyl-oxazolidinones as antibacterial agents | Ferrer Internacional, S.A. (ES) | 2010-01-06 | — | — | EP | claimed |
| EP-2324016-B1 | 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | FERRER INT (ES) | 2012-04-25 | — | — | EP | disclosed |
| US-20110136829-A1 | 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | FERRER INTERNACIONAL, S.A. (ES) | 2011-06-09 | — | — | US | disclosed |
| EP-2141162-A1 | 3-(n-heterocyclyl)-pyrrolidinyl-phenyl-oxazolidinones as antibacterial agents | Ferrer Internacional, S.A. (ES) | 2010-01-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136829-A1 | 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | OXA1L, MRPL21, RPL5 | MAOA 1983/4885MAOB 1397/4885PTGS1 1091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.