Tazomeline

Tazomeline

SCHEMBL195235

CCCCCCSc1nsnc1C1=CCCN(C)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 10/20 0.91
CHRM4 P08173 3/20 0.91

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6911698 1.00 CHRM1 (0.91) CHRM1CHRM4
SCHEMBL6915120 1.00 CHRM1 (0.91) CHRM1CHRM4
SCHEMBL6912246 0.99 CHRM1 (0.90) CHRM1CHRM4
SCHEMBL6915565 0.95 CHRM1 (0.88) CHRM1CHRM4
SCHEMBL8189336 0.95 CHRM1 (1.00) CHRM1CHRM4
SCHEMBL8189299 0.95 CHRM1 (1.00) CHRM1CHRM4
SCHEMBL8196563 0.94 CHRM1 (1.00) CHRM1CHRM4
Oxalic Acid SCHEMBL7619270 0.94 CHRM1 (0.79) CHRM1CHRM4
Tazomeline SCHEMBL7615741 0.94 CHRM1 (0.79) CHRM1CHRM4
Oxalic Acid SCHEMBL7642910 0.94 CHRM1 (0.79) CHRM1CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250186415-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT 2025-06-12 US claimed
EP-4489858-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS Harrow IP, LLC (US) 2025-01-15 EP claimed
WO-2023172240-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS HARROW IP, LLC (US) 2023-09-14 WO claimed
US-20190314354-A1 MUSCARINIC COMBINATIONS AND THEIR USE FOR COMBATING HYPOCHOLINERGIC DISORDERS OF THE CENTRAL NERVOUS SYSTEM CHASE PHARMACEUTICALS CORPORATION (US) 2019-10-17 US claimed
US-20180050008-A1 OXYBUTYNIN TRANSDERMAL THERAPEUTIC SYSTEM MUSCARINIC AGONIST COMBINATION CHASE PHARMACEUTICALS CORPORATION (US) 2018-02-22 US claimed
US-20180050018-A1 PERIPHERAL-ANTICHOLINERGIC MUSCARINIC AGONIST COMBINATION CHASE PHARMACEUTICALS CORPORATION (US) 2018-02-22 US claimed
EP-3265128-A1 OXYBUTYNIN TRANSDERMAL THERAPEUTIC SYSTEM MUSCARINIC AGONIST COMBINATION Chase Pharmaceuticals Corporation (US) 2018-01-10 EP claimed
EP-3265466-A1 PERIPHERAL-ANTICHOLINERGIC MUSCARINIC AGONIST COMBINATION Chase Pharmaceuticals Corporation (US) 2018-01-10 EP claimed
US-20160375001-A1 MUSCARINIC COMBINATIONS AND THEIR USE FOR COMBATING HYPOCHOLINERGIC DISORDERS OF THE CENTRAL NERVOUS SYSTEM CHASE PHARMACEUTICALS CORPORATION (US) 2016-12-29 US claimed
WO-2016144719-A1 OXYBUTYNIN TRANSDERMAL THERAPEUTIC SYSTEM MUSCARINIC AGONIST COMBINATION CHASE THOMAS N (US) 2016-09-15 WO claimed
WO-1996025042-A1 TRANSDERMAL FORMULATION ELI LILLY AND COMPANY (US) 1996-08-22 WO claimed
EP-0727209-A2 Transdermal formulation of a compound having muscarinic activity ELI LILLY AND COMPANY (US) 1996-08-21 EP claimed
WO-1996014066-A1 A METHOD OF TREATING URINARY BLADDER DYSFUNCTIONS NOVO NORDISK A/S (DK) 1996-05-17 WO claimed
WO-1996013168-A1 METHOD FOR TREATING ANXIETY ELI LILLY AND COMPANY (US) 1996-05-09 WO claimed
EP-0709095-A2 Method for treating anxiety using a tetrahydropyridine or azabicyclic oxadiazole or thiadiazole compound ELI LILLY AND COMPANY (US) 1996-05-01 EP claimed
US-5488056-A 1,2,5-THIADIAZOLE COMPOUNDS ELI LILLY AND COMPANY (US) 1996-01-30 US claimed
EP-0384288-B1 Piperidine compounds and their preparation and use NOVO NORDISK AS (DK) 1995-05-24 EP claimed
WO-1995005174-A1 ANTIPSYCHOTIC METHOD NOVO NORDISK A/S (DK) 1995-02-23 WO claimed
US-5041455-A Stimulants of cognitive function in mammals NOVO NORDISK A/S (DK) 1991-08-20 US claimed
EP-0384288-A2 Piperidine compounds and their preparation and use NOVO NORDISK A/S (DK) 1990-08-29 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180050018-A1 PERIPHERAL-ANTICHOLINERGIC MUSCARINIC AGONIST COMBINATION CHRM3, CHRM2, CHRM4 CHRM1 7/4885CHRM4 3/4885
US-20190314354-A1 MUSCARINIC COMBINATIONS AND THEIR USE FOR COMBATING HYPOCHOLINERGIC DISORDERS OF THE CENTRAL NERVOUS SYSTEM CHRM3, CHRM2, CHRM4 CHRM1 5/4885CHRM4 3/4885
US-20160375001-A1 MUSCARINIC COMBINATIONS AND THEIR USE FOR COMBATING HYPOCHOLINERGIC DISORDERS OF THE CENTRAL NERVOUS SYSTEM CHRM3, CHRM2, CHRM4 CHRM1 5/4885CHRM4 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.