Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 11/20 | 1.00 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.97 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8189336 | 0.99 | CHRM1 (1.00) | CHRM1CHRM4SIGMAR1 | |
| SCHEMBL8189299 | 0.99 | CHRM1 (1.00) | CHRM1CHRM4SIGMAR1 | |
| SCHEMBL8196549 | 0.97 | CHRM1 (1.00) | CHRM1CHRM4SIGMAR1 | |
| SCHEMBL6912246 | 0.95 | CHRM1 (0.90) | CHRM1CHRM4 | |
| SCHEMBL6911698 | 0.94 | CHRM1 (0.91) | CHRM1CHRM4 | |
| SCHEMBL6940009 | 0.94 | CHRM1 (0.88) | CHRM1CHRM4SIGMAR1 | |
| Tazomeline SCHEMBL195235 | 0.94 | CHRM1 (0.91) | CHRM1CHRM4 | |
| SCHEMBL6915120 | 0.94 | CHRM1 (0.91) | CHRM1CHRM4 | |
| SCHEMBL6916110 | 0.94 | CHRM1 (0.88) | CHRM1CHRM4SIGMAR1 | |
| SCHEMBL6915565 | 0.94 | CHRM1 (0.88) | CHRM1CHRM4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0628041-B1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 2000-07-12 | — | — | EP | claimed |
| US-5977129-A | ALZHEIMER'S DISEASE | NOVO NORDISK A/S (DK) | 1999-11-02 | — | — | US | claimed |
| EP-0628041-A1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1994-12-14 | — | — | EP | claimed |
| WO-1993014089-A1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1993-07-22 | — | — | WO | claimed |
| WO-1993014090-A1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1993-07-22 | — | — | WO | claimed |
| EP-0628041-B1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 2000-07-12 | — | — | EP | disclosed |
| US-5977129-A | ALZHEIMER'S DISEASE | NOVO NORDISK A/S (DK) | 1999-11-02 | — | — | US | disclosed |
| US-5414009-A | Cognition activators, analgesics; Alzheimer's disease, glaucoma | NOVO NORDISK A/S (DK) | 1995-05-09 | — | — | US | disclosed |
| EP-0628041-A1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1994-12-14 | — | — | EP | disclosed |
| WO-1993014089-A1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1993-07-22 | — | — | WO | disclosed |
| WO-1993014090-A1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1993-07-22 | — | — | WO | disclosed |