Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 6/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Posatirelin SCHEMBL3083636 | 1.00 | TRHR (0.68) | TRHR | |
| SCHEMBL27830909 | 0.95 | TRHR (0.66) | TRHR | |
| SCHEMBL1371608 | 0.95 | TRHR (0.66) | TRHR | |
| SCHEMBL11182741 | 0.95 | TRHR (0.66) | TRHR | |
| SCHEMBL11179550 | 0.95 | TRHR (0.66) | TRHR | |
| SCHEMBL11331704 | 0.95 | TRHR (0.66) | TRHR | |
| SCHEMBL11174568 | 0.88 | TRHR (0.70) | TRHR | |
| SCHEMBL11328954 | 0.86 | TRHR (0.54) | TRHR | |
| SCHEMBL11179368 | 0.85 | TRHR (0.66) | TRHR | |
| SCHEMBL11333599 | 0.85 | TRHR (0.54) | TRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 368 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230135373-A1 | METHODS AND COMPOSITIONS FOR TREATING SLEEP APNEA | APNIMED, INC. (DELAWARE) | 2023-05-04 | — | — | US | claimed |
| US-20210346621-A1 | INTRANASAL ADMINISTRATION | Optinose, Inc. | 2021-11-11 | — | — | US | claimed |
| WO-2021202906-A1 | METHODS AND COMPOSITIONS FOR TREATING SLEEP APNEA | APNIMED, INC. (DELAWARE) (US) | 2021-10-07 | — | — | WO | claimed |
| US-20200103419-A1 | BLOOD BIOMARKERS AND DIAGNOSTIC METHODS FOR SMALL VESSEL DISEASES | THE SCHEPENS EYE RESEARCH INSTITUTE, INC. | 2020-04-02 | — | — | US | claimed |
| US-20190125992-A1 | INTRANASAL ADMINISTRATION | OptiNose Inc. | 2019-05-02 | — | — | US | claimed |
| WO-2018183213-A1 | BLOOD BIOMARKERS AND DIAGNOSTIC METHODS FOR SMALL VESSEL DISEASES | THE SCHEPENS EYE RESEARCH INSTITUTE, INC. (US) | 2018-10-04 | — | — | WO | claimed |
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| US-20100226943-A1 | SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL | UNIVERSITY OF FLORIDA (US) | 2010-09-09 | — | — | US | claimed |
| US-20100035805-A1 | NON-AQUEOUS LIQUID FORMULATION FOR NASAL OR BUCCAL ADMINISTRATION | OPTINOSE AS (NO) | 2010-02-11 | — | — | US | claimed |
| WO-2009005519-A1 | COMBINATIONS OF MEDIUM CHAIN TRIGLYCERIDES AND THERAPEUTIC AGENTS FOR THE TREATMENT AND PREVENTION OF ALZHEIMER'S DISEASE AND OTHER DISEASES RESULTING FROM REDUCED NEURONAL METABOLISM | ACCERA, INC. (US) | 2009-01-08 | — | — | WO | claimed |
| WO-2007061529-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | SCIDOSE LLC. (US) | 2007-05-31 | — | — | WO | claimed |
| US-20070116729-A1 | Lyophilization process and products obtained thereby | SCIDOSE LLC | 2007-05-24 | — | — | US | claimed |
| EP-1032402-B1 | Use of citicoline for the treatment of multiple sclerosis (MS) | INTERNEURON PHARMA (US) | 2004-02-25 | — | — | EP | claimed |
| EP-0572942-B2 | Oral pharmaceutical compositions for specific colon delivery | MONSANTO IT SPA (IT) | 2000-11-29 | — | — | EP | claimed |
| US-5759566-A | ETHYLENE OXIDE-PROPYLENE OXIDE COPOLYMER THICKENER | POLI INDUSTRIA CHIMICA SPA (IT) | 1998-06-02 | — | — | US | claimed |
| US-5654000-A | LIQUID MIXTURE OF A LIPOSOMIC DISPERSION CONTAINING A DRUG AND A THERMOSETTING ETHYLENE OXIDE-PROPYLENE OXIDE COPOLYMER, SUSTAINED RELEASE | POLI INDUSTRIA CHIMICA S.P.A. (IT) | 1997-08-05 | — | — | US | claimed |
| EP-0652744-B1 | PHARMACEUTICAL COMPOSITIONS FOR TRANSMUCOSAL DELIVERY OF PEPTIDES | POLI IND CHIMICA SPA (IT) | 1996-03-20 | — | — | EP | claimed |
| EP-0652744-A1 | PHARMACEUTICAL COMPOSITIONS FOR TRANSMUCOSAL DELIVERY OF PEPTIDES. | POLI IND CHIMICA SPA (IT) | 1995-05-17 | — | — | EP | claimed |
| WO-1994003157-A1 | PHARMACEUTICAL COMPOSITIONS FOR TRANSMUCOSAL DELIVERY OF PEPTIDES | POLI INDUSTRIA CHIMICA S.P.A. (IT) | 1994-02-17 | — | — | WO | claimed |
| EP-0572942-A2 | Oral pharmaceutical compositions for specific colon delivery | POLI INDUSTRIA CHIMICA S.p.A. (IT) | 1993-12-08 | — | — | EP | claimed |