SCHEMBL195277

SCHEMBL195277

O=C(ON1CCCCCC1=O)C1CCCN1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 8/20 0.35
DPP8 Q6V1X1 3/20 0.35
DPP9 Q86TI2 2/20 0.35
FAP Q12884 1/20 0.35
DPP7 Q9UHL4 1/20 0.35
PARP1 P09874 2/20 0.34
HTR2C P28335 2/20 0.33
HTR2B P41595 1/20 0.33
ELANE P08246 1/20 0.32
ANPEP P15144 1/20 0.32
NOS2 P35228 2/20 0.31
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9803421 0.94 DPP4 (0.37) DPP4DPP8DPP9FAPDPP7
SCHEMBL1114767 0.78 DPP4 (0.34) DPP4DPP8DPP9FAPDPP7
SCHEMBL5699875 0.78 DPP4 (0.34) DPP4DPP8DPP9FAPDPP7
SCHEMBL720328 0.78 DPP4 (0.34) DPP4DPP8DPP9FAPDPP7
SCHEMBL5689235 0.77 DPP4 (0.36) DPP4DPP8DPP9FAPDPP7
SCHEMBL9194164 0.77 DPP4 (0.36) DPP4DPP8DPP9FAPDPP7
SCHEMBL4963191 0.77 DPP4 (0.41) DPP4DPP8DPP9FAPDPP7
SCHEMBL444869 0.75 DPP4 (0.42) DPP4DPP8DPP9FAPDPP7
SCHEMBL4961794 0.72 SMN1; SMN2 (0.38)
SCHEMBL27661363 0.72 SMN1; SMN2 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2401610-A1 METHODS FOR IDENTIFICATION Cambridge Enterprise Ltd. (GB) 2012-01-04 EP disclosed
WO-2010097591-A1 METHODS FOR IDENTIFICATION CAMBRIDGE ENTERPRISE LIMITED (GB) 2010-09-02 WO disclosed
EP-1896036-A1 ANTI-INFLAMMATORY AGENTS Cambridge Enterprise Limited (GB) 2008-03-12 EP disclosed
WO-2006134384-A1 ANTI-INFLAMMATORY AGENTS CAMBRIDGE ENTERPRISE LIMITED (GB) 2006-12-21 WO disclosed