Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL444869 | 0.98 | DPP4 (0.42) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL10905658 | 0.85 | DPP4 (0.39) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL28071490 | 0.85 | DPP4 (0.53) | DPP4DPP8DPP9FAPDPP7 | |
| Hydrochloric Acid SCHEMBL28071357 | 0.83 | DPP4 (0.51) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL28407251 | 0.83 | DPP4 (0.36) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL195277 | 0.77 | DPP4 (0.35) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL6859669 | 0.74 | NOS2 (0.46) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL146828 | 0.74 | NOS2 (0.46) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL995604 | 0.74 | NOS2 (0.46) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL27722474 | 0.73 | GABRP (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101163472-A | Vla-4 antagonists | MERCK & CO INC (US) | 2008-04-16 | — | — | CN | disclosed |
| EP-1874299-A2 | VLA-4 ANTAGONISTS | Merck & Co., Inc. (US) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006115918-A2 | VLA-4 ANTAGONISTS | MERCK & CO., INC. (US) | 2006-11-02 | — | — | WO | disclosed |