⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746456 | 1.00 | — | — | |
| SCHEMBL13674461 | 1.00 | — | — | |
| SCHEMBL13407651 | 0.88 | ACHE (0.39) | — | |
| SCHEMBL6902050 | 0.88 | ACHE (0.39) | — | |
| SCHEMBL3543013 | 0.88 | ACHE (0.39) | — | |
| SCHEMBL21896997 | 0.81 | — | — | |
| SCHEMBL13626272 | 0.81 | — | — | |
| SCHEMBL27281914 | 0.80 | — | — | |
| SCHEMBL18117444 | 0.77 | — | — | |
| SCHEMBL14228747 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200123132-A1 | ANTIVIRAL COMPOUNDS | GILEAD PHARMASSET LLC | 2020-04-23 | — | — | US | disclosed |
| EP-3239152-A1 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2017-11-01 | — | — | EP | disclosed |