⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6782 | 0.96 | — | — | |
| SCHEMBL787284 | 0.93 | — | — | |
| SCHEMBL439660 | 0.93 | — | — | |
| SCHEMBL107064 | 0.93 | — | — | |
| SCHEMBL8668896 | 0.93 | — | — | |
| SCHEMBL1024872 | 0.93 | — | — | |
| SCHEMBL16193434 | 0.93 | — | — | |
| SCHEMBL7806168 | 0.93 | — | — | |
| SCHEMBL21405143 | 0.93 | — | — | |
| SCHEMBL104508 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772087-A | Preparation process of furanone | 福建省沙县青州日化有限公司 | 2024-10-15 | — | — | CN | claimed |
| US-8729291-B2 | Method for producing urethanes composed of di-functional aromatic amines and dialkyl carbonates | BASF SE (DE) | 2014-05-20 | — | — | US | claimed |
| CN-118772087-A | Preparation process of furanone | 福建省沙县青州日化有限公司 | 2024-10-15 | — | — | CN | disclosed |
| US-12083121-B2 | Substituted piperazines as KRAS G12C inhibitors | AMGEN INC. (US) | 2024-09-10 | — | — | US | disclosed |
| US-20240246934-A1 | QUINAZOLINE-BASED COMPOUND, COMPOSITION, AND APPLICATION OF QUINAZOLINE-BASED COMPOUND | BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED (CN) | 2024-07-25 | — | — | US | disclosed |
| CN-115109036-B | Quinazoline compound, composition and application thereof | 北京赛特明强医药科技有限公司 | 2024-06-11 | — | — | CN | disclosed |
| EP-4293016-A1 | QUINAZOLINE-BASED COMPOUND, COMPOSITION, AND APPLICATION OF QUINAZOLINE-BASED COMPOUND | Beijing Scitech-MQ Pharmaceuticals Limited (CN) | 2023-12-20 | — | — | EP | disclosed |
| CN-116574134-A | Cyclotriphosphazene derivative containing hydroxyl and ethoxy and preparation method thereof | 云南云天化股份有限公司 | 2023-08-11 | — | — | CN | disclosed |
| WO-2022194265-A1 | QUINAZOLINE-BASED COMPOUND, COMPOSITION, AND APPLICATION OF QUINAZOLINE-BASED COMPOUND | 北京赛特明强医药科技有限公司 | 2022-09-22 | — | — | WO | disclosed |
| US-20220175782-A1 | KRAS G12C INHIBITORS AND METHODS OF USING THE SAME | AMGEN INC. | 2022-06-09 | — | — | US | disclosed |
| US-11285156-B2 | Substituted piperazines as KRAS G12C inhibitors | AMGEN INC. (US) | 2022-03-29 | — | — | US | disclosed |
| US-4289879-A | Synthetic method and intermediate for piroxicam | PFIZER INC. (US) | 1981-09-15 | — | — | US | disclosed |
| US-4258033-A | CORONARY VASODILATORS EFFECTIVE IN ISCHEMIC HEART DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-03-24 | — | — | US | disclosed |
| US-4258173-A | Polyphosphazene polymers containing monoetheroxy and polyetheroxy substituents | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1981-03-24 | — | — | US | disclosed |
| US-4255565-A | REACTION OF 5-AMINO-1-B-D-RIBOFURANOSYL-4-CYANOIMIDAZOLE AND AN N-CARBO-SUBSTITUTED CYANAMIDE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-03-10 | — | — | US | disclosed |
| US-4225591-A | CORONARY VASODILATOR | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1980-09-30 | — | — | US | disclosed |
| EP-0008795-A1 | Polyphosphazene polymers containing monoetheroxy and polyetheroxy substituents | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1980-03-19 | — | — | EP | disclosed |
| US-4152356-A | SELECTIVE CARBONYLATION OF 9,10-DIHYDROANTHRACENE TO FORM 9-FORMYL-9,10-DIHYDROANTHRACENE | EXXON RESEARCH & ENGINEERING CO. (US) | 1979-05-01 | — | — | US | disclosed |
| US-4082810-A | STEREOSELECTIVE HYDROGENATING AGENTS | ALDRICH-BORANES, INC. (US) | 1978-04-04 | — | — | US | disclosed |
| US-4059615-A | INSECTICIDE, POLYMER INTERMEDIATE | HOOKER CHEMICALS & PLASTICS CORPORATION (US) | 1977-11-22 | — | — | US | disclosed |