Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CCNC | P24863 | 2/20 | 0.44 |
| ▸ | CDK8 | P49336 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 2/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19544299 | 0.81 | HPGD (0.46) | HPGDMAPK1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL19533645 | 0.72 | ALDH1A1 (0.50) | HPGDMAPK1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL300831 | 0.69 | HPGD (0.68) | HPGDMAPK1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL10721733 | 0.68 | HPGD (0.95) | HPGDMAPK1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL7901274 | 0.68 | HPGD (0.71) | HPGDALDH1A1KDM4EL3MBTL1MEN1 | |
| SCHEMBL21321950 | 0.68 | HPGD (0.71) | HPGDALDH1A1KDM4EL3MBTL1MEN1 | |
| SCHEMBL1424454 | 0.67 | HPGD (0.76) | HPGDMAPK1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL7132525 | 0.66 | HPGD (1.00) | HPGDMAPK1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL27479149 | 0.66 | HPGD (1.00) | HPGDMAPK1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL10264405 | 0.66 | ALDH1A1 (0.62) | HPGDALDH1A1KDM4EL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170313683-A1 | BTK INHIBITOR | HUBEI BIO-PHARMACEUTICAL INDUSTRIAL TECHNOLOGICAL INSTITUTE, INC. (CN) | 2017-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170313683-A1 | BTK INHIBITOR | BTK, SYK, LYN | HPGD 4511/4885MAPK1 331/4885ALDH1A1 4122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.