Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7172382 | 0.79 | CSNK2A1 (0.59) | CSNK2A1TSHRRORCMAPK1SMN1; SMN2 | |
| SCHEMBL254820 | 0.78 | TSHR (0.64) | CSNK2A1TSHRHTR2AHTR2CHTR2B | |
| SCHEMBL1332160 | 0.77 | TRPV4 (0.46) | MAPK1POLBCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10540450 | 0.76 | TTR (0.47) | SMN1; SMN2ADORA3SLC6A4CYP1A2CYP3A4 | |
| SCHEMBL16952522 | 0.76 | CSNK2A1 (0.43) | CSNK2A1TSHRHTR2AHTR2CHTR2B | |
| SCHEMBL339511 | 0.76 | CSNK2A1 (0.43) | CSNK2A1TSHRHTR2AHTR2CHTR2B | |
| SCHEMBL19088280 | 0.76 | TRPV4 (0.46) | CSNK2A1TSHRHTR2AHTR2CHTR2B | |
| SCHEMBL339512 | 0.76 | CSNK2A1 (0.43) | CSNK2A1TSHRHTR2AHTR2CHTR2B | |
| SCHEMBL14986712 | 0.76 | CSNK2A1 (0.43) | CSNK2A1TSHRHTR2AHTR2CHTR2B | |
| SCHEMBL359023 | 0.76 | MAPT (0.52) | CSNK2A1TSHRHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017189613-A1 | METHODS OF USING FASN INHIBITORS | FORMA THERAPEUTICS, INC. (US) | 2017-11-02 | — | — | WO | disclosed |