SCHEMBL19542829

SCHEMBL19542829

C=CC1CCC(C2CCC(c3ccc(OCCF)cc3)CC2)CC1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 9/20 0.38
KCNH2 Q12809 4/20 0.38
CYP3A4 P08684 3/20 0.38
CYP2C9 P11712 3/20 0.38
HTR1A P08908 1/20 0.36
DRD2 P14416 1/20 0.36
DRD1 P21728 1/20 0.36
DRD5 P21918 1/20 0.36
HTR2A P28223 1/20 0.36
DRD3 P35462 1/20 0.36
FAAH O00519 1/20 0.36
APP P05067 2/20 0.35
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19542809 0.93 HRH3 (0.40) HRH3KCNH2CYP3A4CYP2C9HTR1A
SCHEMBL19542808 0.92 HRH3 (0.38) HRH3KCNH2CYP3A4CYP2C9HTR1A
SCHEMBL18310461 0.89 HRH3 (0.34) HRH3KCNH2CYP3A4CYP2C9HTR1A
SCHEMBL19542789 0.85 HRH3 (0.40) HRH3KCNH2CYP3A4CYP2C9HTR1A
SCHEMBL18310393 0.84 HRH3 (0.36) HRH3KCNH2CYP3A4CYP2C9HTR1A
SCHEMBL19850730 0.83 NQO1 (0.41) DRD2RAB9A
SCHEMBL18310443 0.80 HRH3 (0.34) HRH3KCNH2CYP3A4CYP2C9HTR1A
SCHEMBL15274896 0.78 NQO1 (0.45) DRD2RAB9A
SCHEMBL13417726 0.78 DRD2 (0.44) CYP3A4DRD2RAB9A
SCHEMBL15581252 0.78 HRH3 (0.41) HRH3KCNH2CYP3A4CYP2C9HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170313939-A1 LIQUID CRYSTAL COMPOSITION AND ITS APPLICATION BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD (CN) 2017-11-02 US disclosed