Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | CBX4 | O00257 | 2/20 | 0.43 |
| ▸ | CBX7 | O95931 | 2/20 | 0.43 |
| ▸ | CDYL2 | Q8N8U2 | 2/20 | 0.43 |
| ▸ | CBX8 | Q9HC52 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16305983 | 1.00 | PPARG (0.47) | PPARGPPARAITGB1ITGA4ITGB3 | |
| SCHEMBL16306129 | 1.00 | PPARG (0.47) | PPARGPPARAITGB1ITGA4ITGB3 | |
| SCHEMBL16305929 | 0.96 | ITGB3 (0.45) | PPARGPPARAITGB1ITGA4ITGB3 | |
| SCHEMBL16380214 | 0.94 | PPARG (0.48) | PPARGPPARAITGB1ITGA4ITGB3 | |
| SCHEMBL16306044 | 0.94 | PPARG (0.48) | PPARGPPARAITGB1ITGA4ITGB3 | |
| SCHEMBL16380212 | 0.94 | PPARG (0.48) | PPARGPPARAITGB1ITGA4ITGB3 | |
| SCHEMBL16305683 | 0.94 | PPARG (0.47) | PPARGPPARAITGB1ITGA4ITGB3 | |
| SCHEMBL16305682 | 0.94 | ITGB3 (0.53) | PPARGPPARAITGB1ITGA4ITGB3 | |
| SCHEMBL16306205 | 0.94 | PPARG (0.47) | PPARGPPARAITGB1ITGA4ITGB3 | |
| SCHEMBL16305796 | 0.93 | ITGB3 (0.50) | PPARGPPARAITGB1ITGA4ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170313717-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2017-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170313717-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, NPY1R | PPARG 317/4885PPARA 491/4885ITGB1 3589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.